Penn Center for Biomedical Imaging (CBI) is established as a type 1 center in 2011. It serves as a central focus for biomedical imaging research at the University of Pennsylvania. The CBI is organized into a Basic Imaging Research Division, Translational Research Division, and imaging Core Facilities. The Basic Research Division includes laboratories focused on basic imaging methodology. The Translational Division includes programs developed in collaboration with disease oriented centers focused on the application of imaging to basic biomedical research and to advance clinical care. The CBI administration operates a range of core facilities to support investigators interested in biomedical imaging. The cores include clinical MRI, PET, SPECT, US and CT scanners; a comprehensive small animal imaging facility; and support for research coordinators, protocol development and image analysis.