Penn Radiology’s Basic Research Division includes laboratories focused on basic imaging methodology. Our research labs are separated into quantitative, biomedical imaging informatics, and molecular imaging labs.
Studies of the science of information related to medical imaging, including image analysis and the integration of data from medical imaging into scientific research and clinical practice.
The Artificial Intelligence in Biomedical Imaging Lab (AIBIL) focuses on machine learning in neuroimaging, including imaging signatures of brain aging, Alzheimer’s Disease, schizophrenia, and brain cancer, as well as of functional connectivity.
The Center for Biomedical Image Computing and Analytics (CBICA) was established in 2013, and focuses on the development and application of advanced computational and analytical techniques that quantify morphology and function from biomedical images.
Center for Global and Population Health Research
The Diffusion & Connectomics In Precision Healthcare Research (DiCIPHR) Lab aims to develop subject-specific imaging biomarkers paving the way for precision imaging.
The research at INSPire lab is primarily directed towards development, optimization and application of metabolic and physiologic MR imaging techniques in various neuro-oncologic clinical applications.
The Medical Image Processing Group (MIPG) conducts full-time medically relevant research in imaging science and offers training to students and post-doctoral fellows.
Research at The Penn Image Computing and Science Laboratory (PICSL) spans numerous collaborations across a variety of disciplines and includes targeted applications of biomedical image analysis to improve the detection of subtle changes on imaging studies.
Studies of imaging designed for the visualization, characterization, and measurement of biological processes at the molecular and cellular levels as well as therapy guided by either anatomic imaging, molecular imaging, or both.
The Breast Cancer Molecular Imaging Group at Penn Medicine seeks better methods for breast cancer treatment. The lab is supported by a grant from the Susan G. Komen Foundation.
The Breast Cancer Translational Research Group (BCTRG) bench to bedside research program aims to understand differences in cancer DNA repair mechanisms and develop predictive biomarkers for targeted therapy response.
The lab employs a combination of metabolic imaging and spectroscopy and biological methods to probe the role of NAD(H) redox status in diseases and develop metabolic/redox biomarkers for clinical translation.
The Delikatny Lab focuses on imaging methods for the detection of tumors in lung and breast cancer.
The goal of the Functional and Metabolic Imaging Group (FMIG) is the development and application of novel hyperpolarized MRI techniques capable of diagnosing a variety of pulmonary and metabolic disorders.
The overall goal of the Laboratory of Molecular Imaging is to foster synergistic and symbiotic collaborations between tumor biologists and the imaging community.
The Metabolic and Molecular Imaging of Cardiovascular Diseases (MMICD) Lab develops experimental and therapeutic approaches to treat heart failure and cancer.
The Molecular and Cellular Technologies Lab at Penn Medicine uses a combination of synthetic chemistry, as well as chemical and synthetic biology to address both basic and translational challenges in imaging and therapy.
Research at the Nanomedicine and Molecular Imaging Lab (NAMIL) focuses on the development of novel and multifunctional nanoparticle contrast agents for medical imaging applications.
The Penn Image-Guided Interventions (PIGI) Laboratory is dedicated to the translational investigation of a multitude of topics of interest to interventional radiology as well as the broader medical community.
The Radiopharmaceutical Chemistry and Biology Lab is dedicated to interdisciplinary research across the Radiology Department at Penn Medicine.
The Radiopharmaceutical Chemistry Section focuses on the development of new radiopharmaceuticals that provide diagnostic information on various organs in normal and disease states.
The Radiopharmaceutical Therapy and Companion Diagnostics Group, under the direction of Daniel A. Pryma, MD, operates in close collaboration with the Radiopharmaceutical Chemistry and Biology Lab.
Studies developing and validating novel approaches to acquire and generate medical images as well as methods for deriving quantitative metric form medical images.
The Advanced Cardiovascular Imaging Lab at Penn Radiology is focused on the development of new imaging technologies for cardiovascular disease.
The Center for Functional Neuroimaging (CFN) provides support for functional neuroimaging research at the University of Pennsylvania.
The Center for Imaging Research with Radiation in Radiology seeks to merge innovative technology with expertise in preclinical and clinical applications in the space of biomedical imaging with radiation.
The Center for Magnetic Resonance and Optical Imaging is a Biomedical Imaging research center dedicated to the development and application of magnetic and optical imaging techniques.
The Laboratory for Advanced Computed Tomography Imaging (LACTI) is dedicated to developing next generation computed tomography solutions.
The Laboratory for Structural, Physiologic and Functional Imaging is focused on the development of new methods of the MR-based "virtual bone biopsy" and image-based computational biomechanics.
The group's research in PET instrumentation development spans basic detector design and modeling to system design and image evaluation.
The Department of Radiology at the University of Pennsylvania houses a state-of-the-art Ultrasound Research Laboratory for conducting clinical and pre-clinical research.
The central focus of the lab is the development of advanced methods for breast cancer imaging including digital mammography and digital breast tomosynthesis (DBT).
The IMPACT lab is dedicated to developing CT and cone-beam CT imaging technologies guided by a rigorous understanding of imaging science.