Department of Radiology


The Laboratory for Advanced Computed Tomography Imaging is dedicated to developing next generation x-ray and computed tomography solutions to provide clinicians with information that exceeds present clinical standards.

When it comes to diagnostics and therapy monitoring, the current tendency is to look at simple "gray values" and contrast differences to determine whether anatomical or pathological changes have occurred. Our long-term vision is to play an active role in the fundamental transformation of x-ray-based imaging towards a diagnostics and therapy tool assisting on the biomolecular level with novel contrast mechanisms.

We address the whole imaging chain by employing cross-discipline approaches, ranging from novel x-ray detection concepts to machine-learning algorithms. Our strong collaboration with experts in clinical departments and the medical device industry guides and accelerates the translation of novel technologies into early clinical applications. The Laboratory for Advanced Computed Tomography Imaging is located in the Department of Radiology of the Perelman School of Medicine at the University of Pennsylvania.


Peter B. Noel, PhD

Peter B. Noël, PhD

Dr. Noël earned Bachelor's and Master's degrees in Biomedical Engineering from the University of Applied Sciences in Giessen, Germany. While conducting research in the area of interventional x-ray imaging at the Toshiba Stroke Research Center (Buffalo, NY), he received a Master's Degree in Computer Science. In 2009, he finalized his Ph.D. in Computer Science from the State University of New York at Buffalo with a focus on advanced 3-D reconstruction algorithms for neuro-interventional applications. Subsequently, he joined the Department of Diagnostic and Interventional Radiology at the Technical University of Munich and established the Laboratory for Advanced Computed Tomography Imaging. He then went on to become Assistant Professor of Medical Physics and department­-wide director of CT research.

In 2018, Dr. Noël joined the Basic Research Division at the Department of Radiology of the Perelman School of Medicine at the University of Pennsylvania as Assistant Professor of Radiology and Director of Computed Tomography Research.

His primary research interests currently include spectral imaging with photon-counting detectors, advanced x-ray tube concepts, phase-contrast and darkfield imaging, reconstruction approaches, and the clinical translation of advanced technologies. His work has found application in oncology, pulmonary disease, cardiovascular disease and osteoporosis screening.

Dr. Noël's publication record not only includes more than 110 peer-reviewed publications in international journals, but also a patent portfolio in the areas of x-ray and CT imaging. He has been named to the editorial board of European Radiology for the medical physics section and is member of both national and international scientific organizations.

Open Positions

Scientist or Postdoctoral Researcher in Biomedical Imaging
Dr. Noël's Laboratory for Advanced Computed Tomography Imaging in the Radiology Department of the University of Pennsylvania seeks a full-time postdoctoral researcher with expertise in biomedical imaging. A candidate for this position should hold a Ph.D. in one of the following or closely related fields: physics, bioengineering, computer sciences, mechanical engineering, or electrical engineering. Prior work experience in the area of biomedical imaging is highly desirable. A strong background in x-ray imaging, image reconstruction, and/or machine learning is a plus. The applicant should be highly motivated, exhibit excellent interpersonal and communication skills, and be able to prioritize multiple tasks.

Mechanical Engineer in Biomedical Imaging
A candidate for this position should hold a Bachelor's degree in Mechanical, Manufacturing, Electrical Engineering or a related field. Duties of this position include design, optimization and implementation of experimental x-ray and CT imaging setups. Additional duties will be to keep laboratory space in safe and operational working order. The successful candidate will have demonstrated the ability to work independently and meet objectives in a timely manner. Knowledge of 3-D printing and CAD modelling is a plus.

Undergraduates and Master's students as well as individuals seeking a visiting research fellowship, are also encouraged to contact Dr. Noël about working in the Laboratory for Advanced Computed Tomography Imaging.

All applicants should send an email with attached CV explaining their interest in the position to Dr. Noël.

Contact Information

Dr. Peter Noël
Laboratory for Advanced Computed Tomography Imaging
University of Pennsylvania
Department of Radiology
3400 Spruce Street, One Silverstein
Philadelphia, PA 19104
Office: +1 (215) 898-8212

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