Our research faculty lead diverse programs funded by the National Institutes of Health, foundations, and corporate sponsors with in the rich of environment of the Perelman School of Medicine. These programs leverage Penn's many institutes and centers, including the Penn Cardiovascular Institute, the Institute for Translational Medicine and Therapeutics, the Institute for Diabetes, Obesity and Metabolism, the Leonard Davis Institute for Health Economics, and the Center for Clinical Epidemiology and Biostatistics. Please see below for more detail.
The Arany lab pursues a mechanistic understanding of metabolism in the cardiovascular system, and its impact on diabetes, heart failure, and other metabolic diseases. The lab incorporates a wide range of approaches, from basic molecular biology to human genetics and whole-organism metabolism.
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The Cappola Lab focuses on heart failure mechanisms, genomics, and therapeutics with an emphasis on studies in human subjects
The Epstein Lab focuses on stem cell and developmental biology with an emphasis on epigenetics and nuclear architecture.
The Jain Lab deciphers basic mechanisms regulating specification and differentiation of cells composing the heart. We also investigate how these mechanisms inform emerging cardiac regenerative approaches and therapeutics.
Learn more about the Jain Lab
The Kahn Lab investigates many aspects of vascular and cardiovascular biology, including blood and lymphatic vascular development and disease, and the role of fluid forces in cardiovascular biology, and hemostasis.
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The Kelly Lab is interested in the control of energy metabolism and mitochondrial function in the developing and diseased heart.
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The Ky Lab is interested in understanding the biologic and functional cardiovascular effects of cancer therapies in humans.
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Dr. Kimmel performs research aimed at improving the use of existing cardiovascular therapies through personalized medicine, behavioral interventions, and novel adherence methods.
- Steven Kimmel, MD
Professor of Medicine and Epidemiology; Director, Division of Clinical Epidemiology
Director, Center for Therapeutic Effectiveness Research (CTER)
Learn more about the Center for Therapeutic Effectiveness Research (CTER)
The Margulies Lab examines mechanisms of myocardial structural and functional remodeling to identify targets for therapeutic interventions.
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The goal of the Morrisey Lab is to define the molecular mechanisms underlying lung and cardiac development and tissue regeneration using a multi-platform approach including animal and human model systems.
- Edward Morrisey, PhD
Professor of Cell and Developmental Biology
Director, Penn Center for Pulmonary Biology
The Robinette Foundation Professor of Cardiovascular Medicine
Scientific Director, Penn Institute for Regenerative Medicine
Learn more about the Morrisey Lab
The Musunuru Lab focuses on the genetics of cardiovascular and metabolic diseases and seeks to identify naturally occurring genetic variants that predispose to or protect against disease and can be used to develop therapies to protect the entire population.
The Scherrer-Crosbie Lab is interested in better understanding and detecting subclinical myocardial disease in cancer and in metabolic and adipose dysfunction.