Thomas P. Cappola, MD, ScM

Kim M, Subramanian V, Tavolinejad H, Sarmiento Bustamante M, Pourmussa B, Mann DL, Javaheri A, Richards AM, Doughty RN, Rietzschel E, van Empel V, Zamani P, Cappola TP, Tong D, Chung S, Pandey A, Chirinos JA. Clonal Hematopoiesis of Indeterminate Potential Proteomic Risk Score for Predicting Clinical Outcome in Patients With Heart Failure With Preserved Ejection Fraction. , Circ Heart Fail: 2026,doi: 10.1161/CIRCHEARTFAILURE.126.014345

Zelleke AB, Azzo JD, Moreno JD, Mann DL, Cappola TP, Chirinos JA, Javaheri A. RACGAP1 as a Circulating Biomarker of Atrial Fibrillation in Heart Failure: A Dual-Cohort Proteomic Study , Circ Arrhythm Electrophysiol, 19(5): 2026,e014024

Skarke C, El Jamal N, Genuardi MV, Brooks TG, Mrčela A, Lahens NF, Cordoza M, Sarles S, Mbadugha A, Karunamuni DR, Gupta S, Bae CJ, Sehgal A, Cappola TP, Gutsche JT, Atluri P, Desai ND, Acker MA, Grant GR, Schwab RJ, Rosen IM, FitzGerald GA. Quantifying sleep wake rhythms in the hospital environment with digital technologies , NPJ Digit Med, 9(1): 2026,479

Vidula MK, Schurgers LJ, Zhao L, Dib MJ, Zhao M, Wang Z, Ebert C, Salman O, Azzo JD, Zamani P, van Empel V, Richards AM, Doughty R, Javaheri A, Mann DL, Rietzschell E, Kammerhoff K, Schafer P, Seiffert DA, Ramirez-Valle F, Cappola TP, Chirinos JA. Dephospho-Uncarboxylated Matrix Gla-Protein Is Associated With Adverse Outcomes in Heart Failure. , Circ Heart Fail, 19(2): 2026,e012734

Mann DL, Chirinos JA, Yu J, Yang W, McNamara DM, Richards B, Taddei-Peters WC, Jeffries N, Stewart GC, Qian C, Cappola TP, Aaronson KD; REVIVAL Investigators. Circulating Proteomic Profiles in Ambulatory Patients With Advanced Stage C2D Heart Failure: Insights From the Registry Evaluation of Vital Information for VADs in Ambulatory Life (REVIVAL) Registry. , J Card Fail, 32(8): 2026,1451-1455

Abramowitz SA, Hoffman-Andrews L, Zhang D, Judy R, Cappola TP, Day SM, Reza N, Owens AT, Damrauer SM, Levin MG; Penn Medicine BioBank Polygenic background and penetrance of pathogenic variants in hypertrophic and dilated cardiomyopathies. , JAMA Cardiol: 2025,e254739

Vajargah KK, Dib MJ, Tavolinejad H, Zamani P, Richards AM, Mann DL, Rietzschel E, van Empel V, Burgess S, Cappola TP, Chirinos JA. Proteome-Wide Genetic Investigation of Kidney Function in Heart Failure With Preserved Ejection Fraction. , JACC Heart Fail: 2025,102771

Woerner J, Westbrook TM, Joo J, Shivakumar M, Venkatesh R, Cherlin T, Jung SH, Jeong S, Maseda D, McKeague M, Shwetank, Ionita M, Wagenaar J, Abramowitz SA, Verma A, Zhao B, Lee S, Damrauer S, Levin MG, Heo SC, Cappola TP, Rader DJ, Day S, Deo R, Gelfand JM, Ramessur R, Guerraty MA, Setia-Verma S, Pasaniuc B, Ritchie MD, Apostolidis SA, Greenplate AR, Wherry EJ; Penn Medicine Biobank; Nam Y, Kim D. Large-scale evaluation of proteomic and polygenic risk scores reveals complementary contributions to incident disease prediction. , medRxiv [Preprint]: 2025,25331242

Lindholm ME, Abramowitz S, Waggott DM, Grove ME, Dewey FE, Pan C, Pavlovic A, Shang C, Huang Y, Bensabath L, Goldfeder RL, Cordero P, Erbilgin A, Priest JR, Chaib H, Puckelwartz MJ, Day SM, McNally EM, Cappola T, Dorn GW, Ashley EA, Wheeler MT Identification of candidate cardiomyopathy modifier genes through genome sequencing and RNA profiling , Front Cardiovasc Med, 12: 2025,1546493

Wang Q, Tang TM, Youlton M, Weldy CS, Kenney AM, Ronen O, Hughes JW, Chin ET, Sutton SC, Agarwal A, Li X, Behr M, Kumbier K, Moravec CS, Tang WHW, Margulies KB, Cappola TP, Butte AJ, Arnaout R, Brown JB, Priest JR, Parikh VN, Yu B, Ashley EA Epistasis regulates genetic control of cardiac hypertrophy , Nat Cardiovasc Res, 4(6): 2025,740