About me
- Director, Cardiometabolic Program, Cardiovascular Institute and Institute for Diabetes, Obesity, and Metabolism
- Samuel Bellet Professor of Cardiology
- Professor of Medicine in Cell and Developmental Biology
- Professor of Physiology
My Locations
Qualifications and experience
- Abrax, International
- American Diabetes Association, National
- American Heart Association, National
- American Medical Association, National
- American Society for Clinical Investigation, National
- Association American Physicians, International
- Biohaven, National
- International Society for Heart Research, International
- Interurban Club, National
- Kern Lipid Conference, International
- Keystone Symposia, International
- Massachusetts Medical Society, National
- Nanophoria, International
- National Academy of Medicine, National
- North American Vascular Biology Organization, International
- Scipher, National
Treatments and Conditions
My research
McAfee Q, Chen CY, Yang Y, Caporizzo MA, Morley M, Babu A, Jeong S, Brandimarto J, Bedi KC Jr, Flam E, Cesare J, Cappola TP, Margulies K, Prosser B, Arany Z. Truncated titin proteins in dilated cardiomyopathy , Sci Transl Med, 13: 2021,eabd7287
Goli, Rahul, Li, Jian, Brandimarto, Jeff, Levine, Lisa D, Riis, Valerie, McAfee, Quentin, DePalma, Steven, Haghighi, Alireza, Seidman, J G, Seidman, Christine E, Jacoby, Daniel, Macones, George, Judge, Daniel P, Rana, Sarosh, Margulies, Kenneth B, Cappola, Thomas P, Alharethi, Rami, Damp, Julie, Hsich, Eileen, Elkayam, Uri, Sheppard, Richard, Alexis, Jeffrey D, Boehmer, John, Kamiya, Chizuko, Gustafsson, Finn, Damm, Peter, Ersboll, Anne S, Goland, Sorel, Hilfiker-Kleiner, Denise, McNamara, Dennis M, IMAC-2 and IPAC Investigators, Arany, Zolt Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy. , Circulation: 2021
Murashige D, Jang C, Neinast M, Edwards JJ, Cowan A, Hyman MC, Rabinowitz JD, Frankel DS, Arany Z. Comprehensive quantification of fuel use by the failing and nonfailing human heart , Science, 370: 2020,364-368
Ibrahim A, Yucel N, Kim B, Arany Z Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport , Cell Metabolism, 4(32): 2020,309-319
Hoshino Atsushi, Wang Wei-Jia, Wada Shogo, McDermott-Roe Chris, Evans Chantell S, Gosis Bridget, Morley Michael P, Rathi Komal S, Li Jian, Li Kristina, Yang Steven, McManus Meagan J, Bowman Caitlyn, Potluri Prasanth, Levin Michael, Damrauer Scott, Wallace Douglas C, Holzbaur Erika L F, Arany Zoltan The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. , Nature, 575(7782): 2019,375-379
Neinast Michael D, Jang Cholsoon, Hui Sheng, Murashige Danielle S, Chu Qingwei, Morscher Raphael J, Li Xiaoxuan, Zhan Le, White Eileen, Anthony Tracy G, Rabinowitz Joshua D, Arany Zoltan Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. , Cell metabolism, 29(2): 2018,417-429.e4
Kim Boa, Jang Cholsoon, Dharaneeswaran Harita, Li Jian, Bhide Mohit, Yang Steven, Li Kristina, Arany Zolt Endothelial pyruvate kinase M2 maintains vascular integrity. , The Journal of clinical investigation, 128(10): 2018,4543-4556
Das Abhirup, Huang George X, Bonkowski Michael S, Longchamp Alban, Li Catherine, Schultz Michael B, Kim Lynn-Jee, Osborne Brenna, Joshi Sanket, Lu Yuancheng, Treviño-Villarreal Jose Humberto, Kang Myung-Jin, Hung Tzong-Tyng, Lee Brendan, Williams Eric O, Igarashi Masaki, Mitchell James R, Wu Lindsay E, Turner Nigel, Arany Zolt, Guarente Leonard, Sinclair David A Impairment of an Endothelial NAD-HS Signaling Network Is a Reversible Cause of Vascular Aging. , Cell, 173(1): 2018,74-89.e20
Ware JS, Li J, Mazaika E, Yasso CM, DeSouza T, Cappola TP, Tsai EJ, Hilfiker-Kleiner D, Kamiya CA, Mazzarotto F, Cook SA, Halder I, Prasad SK, Pisarcik J, Hanley-Yanez K, Alharethi R, Damp J, Hsich E, Elkayam U, Sheppard R, Kealey A, Alexis J, Ramani G, Safirstein J, Boehmer J, Pauly DF, Wittstein IS, Thohan V, Zucker MJ, Liu P, Gorcsan J, McNamara DM, Seidman CE, Seidman JG, Arany Z Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies. , The New England journal of medicine, 374(3): 2016,233-41
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. , Nature medicine, 22(4): 2016,421-6