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Kiran Musunuru, MD, PhD, MPH

Kiran Musunuru, MD, PhD, MPH Researcher

Associate Professor of Medicine in Genetics Associate Professor of Medicine

Dr. Musunuru is employed by Penn Medicine.

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Clinical Specialties


  • Cardiology

Programs & Centers:

  • Heart and Vascular Research

Board Certification:

  • Cardiovascular Disease, 2010

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Weill Medical College of Cornell University
Residency: Brigham and Women's Hospital
Fellowship: Johns Hopkins Hospital
Fellowship: Massachusetts General Hospital


American Heart Association, International American Society of Human Genetics (ASHG), National Inter-Society Coordinating Committee for Practitioner Education in Genomics (ISCC), National National Institutes of Health (study sections), National

Hospital Affiliation

Dr. Musunuru is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Musunuru Kiran, Kathiresan Sekar: Genetics of common, complex coronary artery disease Cell 177 (1): 132-145,2019.

Stellos Konstantinos, Musunuru Kiran: Challenges and advances of CRISPR-Cas9 genome editing in therapeutics Cardiovascular Research 115 (2): e12-e14,2019.

Hill Joseph A, Agewall Stefan, Baranchuk Adrian, Booz George W, Borer Jeffrey S, Camici Paolo G, Chen Peng-Sheng, Dominiczak Anna F, Erol Cetin, Grines Cindy, Gropler Robert J, Guzik Tomasz J, Heinemann Markus K, Iskandrian Ami E, Knight Bradley P, London Barry, Lüscher Thomas F, Metra Marco, Musunuru Kiran, Nallamothu Brahmajee K, Natale Andrea, Saksena Sanjeev, Picard Michael H, Rao Sunil V, Remme Willem J, Rosenson Robert S, Sweitzer Nancy K, Timmis Adam D, Vrints Christiaan J: Medical misinformation: vet the message! Circulation : 2019.

Lv Wenjian, Qiao Lyon, Petrenko, Nataliya, Li Wenjun, Owens Anjali T, McDermott-Roe Chris, Musunuru Kiran: Functional annotation of TNNT2 variants of uncertain significance with genome-edited cardiomyocytes Circulation 138 (24): 2852–2854,2018.

Nagiec Marek M, Duvall Jeremy R, Skepner Adam P, Howe Eleanor A, Bastien Jessica, Comer Eamon, Marie Jean-Charles, Johnston Stephen E, Negri Joseph, Eichhorn Michelle, Vantourout Julien, Clish Clary, Musunuru Kiran, Foley Michael, Perez Jose R, Palmer Michelle A J: Novel tricyclic glycal-based inducers that reprogram LDL metabolism in hepatic cells MedChemComm 9 (11): 1831-1842,2018.

Rossidis Avery C, Stratigis John D, Chadwick Alexandra C, Hartman Heather A, Ahn Nicholas J, Li Haiying, Singh Kshitiz, Coons Barbara E, Li Li, Lv Wenjian, Zoltick Philip W, Alapati Deepthi, Zacharias William, Jain Rajan, Morrisey Edward E, Musunuru Kiran, Peranteau William H: In utero CRISPR-mediated therapeutic editing of metabolic genes Nature Medicine 24 (10): 1513-1518,2018.

Wang Xiao, Musunuru Kiran: Confirmation of causal rs9349379-PHACTR1 expression quantitative trait locus in human-induced pluripotent stem cell endothelial cells Circulation: Genomic and Precision Medicine 11 (10): e002327,2018.

Musunuru Kiran, Arora Pankaj, Cooke John P, Ferguson Jane F, Hershberger Ray E, Hickey Kathleen T, Lee Jin-Moo, Lima João A C, Loscalzo Joseph, Pereira Naveen L, Russell Mark W, Shah Svati H, Sheikh Farah, Wang Thomas J, MacRae Calum A: Interdisciplinary models for research and clinical endeavors in genomic medicine: a scientific statement from the American Heart Association Circulation: Genomic and Precision Medicine 11 (6): e000046,2018.

Li Shuang, Li Mushan, Liu Xiaojian, Yang Yuanyuan, Wei Yuda, Chen Yanhao, Qiu Yan, Zhou Tingting, Feng Zhuanghui, Ma Danjun, Fang Jing, Ying Hao, Wang Hui, Musunuru Kiran, Shao Zhen, Zhao Yongxu, Ding Qiurong: Genetic and chemical screenings identify HDAC3 as a key regulator in hepatic differentiation of human pluripotent stem cells Stem Cell Reports : 2018.

Musunuru Kiran, Bernstein Daniel, Cole F Sessions, Khokha Mustafa K, Lee Frank S, Lin Shin, McDonald Thomas V, Moskowitz Ivan P, Quertermous Thomas, Sankaran Vijay G, Schwartz David A, Silverman Edwin K, Zhou Xiaobo, Hasan Ahmed A K, Luo Xiao-Zhong James: Functional assays to screen and dissect genomic hits: doubling down on the national investment in genomic research Circulation: Genomic and Precision Medicine 11 (4): e002178,2018.

Academic Contact Info

3400 Civic Center Blvd, Bldg 421
11-104 Smilow Center for Translational Research

Philadelphia, PA 19104
Phone: (215) 573-4717