Penn Medicine Provider
Mark L. Kahn, MD
Sees patients age 18 and up
About me
- Edward S. Cooper, M.D./Norman Roosevelt and Elizabeth Meriwether McLure Professor
- Professor of Cell and Developmental Biology
My Locations
Qualifications and experience
- American Association for the Advancement of Science, National
- American Heart Association, National
- American Society for Clinical Investigation, National
- American Society for Hematology Abstract Review Committee, National
- American Society of Hematology, National
- Association of American Physicians, National
- NIH Hematology C (Heme-C) Study Section, National
- NIH Pathology A (PTHA) Study Section, National
- North American Vascular Biology Organization (NAVBO), National
My research
Jabarkheel R, Li L, Frankfurter M, Zhang DY, Gajjar A, Muhammad N, Srinivasan VM, Burkhardt JK, Kahn M Untangling sporadic brain arteriovenous malformations: towards targeting the KRAS/MAPK pathway , Front Surg.: 2024
Ren J, Cui Z, Jiang C, Wang L, Guan Y, Ren Y, Zhang S, Tu T, Yu J, Li Y, Duan W, Guan J, Wang K, Zhang H, Xing D, Kahn ML, Zhang H, Hong T GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas , Am J Hum Genet: 2024
Yuki K, Vallon M, Ding J, Rada CC, Tang AT, Vilches-Moure JG, McCormick AK, Henao Echeverri MF, Alwahabi S, Braunger BM, Ergün S, Kahn ML, Kuo CJ GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism , Development: 2024
Kahn ML CCM Function in the Heart: Working From Outside-In Rather Than Inside-Out , JACC Basic Transl Sci: 2024
Li Y, Girard R, Srinath A, Cruz DV, Ciszewski C, Chen C, Lightle R, Romanos S, Sone JY, Moore T, DeBiasse D, Stadnik A, Lee JJ, Shenkar R, Koskimäki J, Lopez-Ramirez MA, Marchuk DA, Ginsberg MH, Kahn ML, Shi C, Awad IA Transcriptomic signatures of individual cell types in cerebral cavernous malformation , Cell Commun Signal: 2024
Ocskay Z, Bálint L, Christ C, Kahn ML, Jakus Z CCBE1 regulates the development and prevents the age-dependent regression of meningeal lymphatics , Biomed Pharmacother: 2024
Gao S, Thillaikumaran T, Dominguez MH, Giang W, Hayes K, Chen X, Pace J, Bockman J, Jathan D, Sung D, Narayan S, Frankfurter M, Mericko-Ishizuka P, Yang J, Castro M, Potente M, Kahn ML YAP/TAZ signaling in allantois-derived cells is required for placental vascularization , bioRxiv: 2024
Li L, Ren AA, Gao S, Su YS, Yang J, Bockman J, Mericko-Ishizuka P, Griffin J, Shenkar R, Alcazar R, Moore T, Lightle R, DeBiasse D, Awad IA, Marchuk DA, Kahn ML, Burkhardt JK mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice , Stroke: 2023
Gao S, Tang AT, Wang M, Buchholz DW, Imbiakha B, Yang J, Chen X, Hewins P, Mericko-Ishizuka P, Leu NA, Sterling S, August A, Jurado KA, Morrisey EE, Aguilar-Carreno H, Kahn ML Endothelial SARS-CoV-2 infection is not the underlying cause of COVID-19-associated vascular pathology in mice , Front Cardiovasc Med: 2023
Hoofnagle MH, Hess A, Nalugo M, Ghosh S, Hughes SW, Fuchs A, Welsh JD, Kahn ML, Bochicchio GV, Randolph GJ, Leonard JM, Turnbull IR Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness , J Trauma Acute Care Surg: 2023