Penn Medicine Provider
Mark L. Kahn, MD
Sees patients age 18 and up

About me

  • Edward S. Cooper, M.D./Norman Roosevelt and Elizabeth Meriwether McLure Professor
  • Professor of Cell and Developmental Biology

My Locations

Qualifications and experience

My research

Jabarkheel R, Li L, Frankfurter M, Zhang DY, Gajjar A, Muhammad N, Srinivasan VM, Burkhardt JK, Kahn M Untangling sporadic brain arteriovenous malformations: towards targeting the KRAS/MAPK pathway , Front Surg.: 2024


Ren J, Cui Z, Jiang C, Wang L, Guan Y, Ren Y, Zhang S, Tu T, Yu J, Li Y, Duan W, Guan J, Wang K, Zhang H, Xing D, Kahn ML, Zhang H, Hong T GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas , Am J Hum Genet: 2024


Yuki K, Vallon M, Ding J, Rada CC, Tang AT, Vilches-Moure JG, McCormick AK, Henao Echeverri MF, Alwahabi S, Braunger BM, Ergün S, Kahn ML, Kuo CJ GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism , Development: 2024


Kahn ML CCM Function in the Heart: Working From Outside-In Rather Than Inside-Out , JACC Basic Transl Sci: 2024


Li Y, Girard R, Srinath A, Cruz DV, Ciszewski C, Chen C, Lightle R, Romanos S, Sone JY, Moore T, DeBiasse D, Stadnik A, Lee JJ, Shenkar R, Koskimäki J, Lopez-Ramirez MA, Marchuk DA, Ginsberg MH, Kahn ML, Shi C, Awad IA Transcriptomic signatures of individual cell types in cerebral cavernous malformation , Cell Commun Signal: 2024


Ocskay Z, Bálint L, Christ C, Kahn ML, Jakus Z CCBE1 regulates the development and prevents the age-dependent regression of meningeal lymphatics , Biomed Pharmacother: 2024


Gao S, Thillaikumaran T, Dominguez MH, Giang W, Hayes K, Chen X, Pace J, Bockman J, Jathan D, Sung D, Narayan S, Frankfurter M, Mericko-Ishizuka P, Yang J, Castro M, Potente M, Kahn ML YAP/TAZ signaling in allantois-derived cells is required for placental vascularization , bioRxiv: 2024


Li L, Ren AA, Gao S, Su YS, Yang J, Bockman J, Mericko-Ishizuka P, Griffin J, Shenkar R, Alcazar R, Moore T, Lightle R, DeBiasse D, Awad IA, Marchuk DA, Kahn ML, Burkhardt JK mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice , Stroke: 2023


Gao S, Tang AT, Wang M, Buchholz DW, Imbiakha B, Yang J, Chen X, Hewins P, Mericko-Ishizuka P, Leu NA, Sterling S, August A, Jurado KA, Morrisey EE, Aguilar-Carreno H, Kahn ML Endothelial SARS-CoV-2 infection is not the underlying cause of COVID-19-associated vascular pathology in mice , Front Cardiovasc Med: 2023


Hoofnagle MH, Hess A, Nalugo M, Ghosh S, Hughes SW, Fuchs A, Welsh JD, Kahn ML, Bochicchio GV, Randolph GJ, Leonard JM, Turnbull IR Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness , J Trauma Acute Care Surg: 2023


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