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What Is Inverted Papilloma?

Inverted papilloma is a benign but locally aggressive tumor that arises in the nasal cavity and paranasal sinuses. It is usually identified in patients with a history of sinonasal infections. Despite being a benign tumor, approximately 5-12 percent of tumors can convert into a malignant tumor, so inverted papillomas should be treated very aggressively. Symptoms in patients typically begin with complaints similar to chronic rhinosinusitis, including nasal congestion, drainage, headaches and postnasal drip.

Diagnosis of Inverted Papilloma

An inverted papilloma diagnosis is typically confirmed by a biopsy based on concerning features on CT, MRI or endoscopic appearance.

Treatment at Penn

The mainstay of treatment for inverted papilloma is surgery. It is important to go to an experienced surgeon because if not removed completely, inverted papillomas have a high rate of recurrence. Surgical resection is typically performed endoscopically. If any concerning features arise after a surgical resection is performed, such as the development of a possible malignant tumor, patients may need a wider resection or additional treatments such as chemotherapy or radiation therapy.

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