Radiobiology and Imaging Program

Program Leaders: Amit Maity, MD, PhD and Daniel Pryma, MD

The Radiobiology and Imaging Program seeks to advance the understanding of the interaction of ionizing and non-ionizing radiation with cancer and normal tissues. Scientific Aims are to:

  • Develop and characterize agents to improve cancer therapy with radiation
  • Investigate radiobiological or imaging methods of altering or interrogating the immune environment to improve therapeutic response
  • Gain a deeper understanding of the tumor microenvironment (TME) and metabolism with the aim to leverage this understanding to improve therapeutic response
  • Develop novel imaging to optimally guide cancer care
  • Understand the biological effects of protons to optimize their clinical use and determine which patients will benefit most from proton beam therapy

The Program is led by Amit Maity, MD, PhD, Professor and Executive Vice-Chair of the Department of Radiation Oncology, and Daniel Pryma, MD, Associate Professor of Radiology and Chief of the Division of Nuclear Medicine. Drs. Maity and Pryma are NCI-funded researchers who bring their scientific vision to this Program, which is focused on basic and translational research and the development of investigator-initiated trials. Drs. Maity and Pryma expanded the Program’s focus on imaging modalities and theranostics and further enhanced the integration and interplay between radiobiology and imaging. A major development has been the substantial expansion of both translational and clinical studies of proton therapy. 

Radiobiology and Imaging Program Membership