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Track Director: Ian Frank, MD

This track is designed for second year infectious diseases fellows to become experts in the clinical management of patients with HIV infection and viral hepatitis. There are opportunities to work with complex, underserved patient populations both locally and abroad. Our division has a wide range of faculty for mentorship with many opportunities in clinical care and research in the fields of HIV and viral hepatitis. Fellows in the track will be required to pursue a scholarly project and to participate in medical education on core topics in these fields. This track will consist primarily of specialized HIV and viral hepatitis clinics as well as inpatient rotations. This practical training in HIV and Viral Hepatitis may be combined with an advanced degree research training program such as the Master of Science in Clinical Epidemiology (MSCE) or the Master of Science in Health Policy Research (MSHP), if desired.

Clinical Training


The outpatient experience will consist of the fellow’s weekly continuity clinic as well as various specialty HIV clinics. Fellows will manage patient’s antiretroviral therapy, pre-exposure prophylaxis and co-infections such as viral hepatitis and mycobacterial diseases. Sites for the continuity clinics can include the Hospital of the University of Pennsylvania (HUP), Penn Presbyterian Medical Center, and Philadelphia Veterans Affairs Medical Center.


The fellow will spend twelve weeks during the second year of fellowship on inpatient rotations. These can include a primary HIV service with focus on the management of complications of HIV, including opportunistic infections and immune reconstitution syndrome. The second year fellow will be responsible for conducting rounds with medical residents and making management decisions with the support of the attending physician.

Medical Education

The fellow will develop and teach a weekly lecture series on core topics in HIV, viral hepatitis and infectious diseases to medical students and residents. S/he will also give an HIV grand rounds patient case presentation to the division. HIV grand rounds patient cases will consist of HIV case management topics and feature multidisciplinary speakers.

Optional Clinical Opportunities

Specialty Clinics

During the second year of the fellowship, the fellow may participate in a number of additional outpatient clinics in both the community and academic setting.

HIV & Hepatitis B/C Clinics

Fellows can establish a continuity clinic that focuses on treatment of both HIV co-infected and mono-infected patients with hepatitis B and C. The fellow will manage the patient throughout the process of evaluation and treatment of hepatitis C and can obtain fibroscan certification.

Jonathan Lax Center

Fellows can rotate through this medical home model for HIV care which includes behavioral health, substance abuse and treatment for HIV/HCV co-infection. There are specialized clinics for youth and recently incarcerated patients at risk of HIV, offering training in PrEP. They will participate in structured teaching on HIV resistance testing and attending weekly management conferences. For more information:

Clinica Bienestar

Fellows can rotate in this clinic which serves patients with HIV, viral hepatitis and substance abuse in a predominantly Puerto Rican population in an underserved area. The clinic is located within Prevention Point, a needle-exchange clinic, in North Philadelphia. Fellows will have an opportunity to learn about harm reduction as well as opioid replacement therapies. For more information:

Philadelphia Department of Public Health

Fellows can spend additional time beyond their first year in the health department’s TB and STI clinics, which serve HIV-positive patients and those at risk of developing HIV. For more information:

Research Experience

The fellow will design and conduct an independent clinical research project with support from their primary mentor and other collaborators on an ICU-related topic. For fellows who do not intend to pursue training in a degree granting program (e.g., MSCE, MSHP), but would like to learn the fundamentals of research methodology, there is the opportunity to obtain a certificate in clinical research. Fellows may work with members of the ID division or other faculty at the University of Pennsylvania in other specialties as appropriate for their interests. In addition to his/her primary research project, the fellow will have the opportunity to participate in clinical trials, working with mentors in the AIDS Clinical Trials Unit (ACTU), the Penn Center for AIDS Research (CFAR), or the Penn Botswana program.


The fellow will be assigned a primary mentor to help develop career goals and design research project(s), and identify potential additional mentors.

Core Faculty

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