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Ian Frank, MD

Ian Frank, MD Physician

Director, Anti-Retroviral Clinical Research Director, Clinical Core, Penn Center for AIDS Research Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Frank is employed by Penn Medicine.

About Dr. Ian Frank

Recognized in Philadelphia magazine's annual Top Docs issue, 2004 - 2012, and 2014 - 2017

Recognized by America's Top Doctors, 2007, 2008, 2010, 2014

Recognized by Best Doctors in America 2003-2004, 2005-2006, 2007-2008, 2009-2010, 2011-2012, 2013-2014

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Infectious Diseases

Programs & Centers:

Board Certification:

  • Infectious Disease, 1992
  • Internal Medicine, 1983

Clinical Expertise:

  • HIV and AIDS
  • Lesbian, Gay, Bisexual and Transgender Health (LGBT)

Description of Clinical Expertise

HIV and AIDS, Lesbian, Gay, Bisexual and Transgender Health (LGBT)

Practice Locations and Appointments

  • Penn Infectious Diseases

    Perelman Center for Advanced Medicine South Pavilion, 4th Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Dartmouth Medical School
Residency: Saint Joseph's Medical Center
Residency: Graduate Hospital
Fellowship: Hospital of the University of Pennsylvania


Adult AIDS Clinical Trials Group, National American Association for the Advancement of Science, National American Federation for Clinical Research, National American Society of Microbiology, National HIV Vaccine Trials Network, International Infectious Diseases Society of America, International International AIDS Society, International National Institute of Allergy and Infectious Diseases Investigator Initiated Program Project Review Committee, ZAI1 JBS-A, National National Institute of Allergy and Infectious Diseases, Centers for AIDS Research and Developmental Center for AIDS Research Meeting, ZAI1 JRR-A (J3) study section, National NIH AIDS Clinical Studies and Epidemiology Study Section, National NIH AIDS Research Review Committee (AIDSRRC) Study Section , National NIH AIDS Research Review Committee (AIDSRRC) Study Section , National NIH Challenge Grants Panel 1, National NIH Challenge Grants Panel 24, National Philadelphia Field Initiating Group for HIV Trials , Local

Hospital Affiliation

Dr. Frank is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Fishman J, Taylor L, Frank I: Awareness of HPV and Uptake of Vaccination in a High-Risk Population Pediatrics 138 (2): 2016.

Bednar MM, Hauser BM, Zhou S, Jacobson JM, Eron JJ, Frank I, Swanstrom R: Diversity and Tropism of HIV-1 Rebound Virus Populations in Plasma Level After Treatment Discontinuation The Journal of infectious diseases 214 (3): 403-7,2016.

Ravimohan S, Tamuhla N, Nfanyana K, Steenhoff AP, Letlhogile R, Frank I, MacGregor RR, Gross R, Weissman D, Bisson GP: Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome Clin Infect Dis 62 (6): 795-803,2016.

Dinges Warren, Girard Pierre-Marie, Podzamczer Daniel, Brockmeyer Norbert H, García Felipe, Harrer Thomas, Lelievre Jean-Daniel, Frank Ian, Colin De Verdière Nathalie, Yeni Guy-Patrick, Ortega Gonzalez Enrique, Rubio Rafael, Clotet Sala Bonaventura, DeJesus Edwin, Pérez-Elias Maria Jesus, Launay Odile, Pialoux Gilles, Slim Jihad, Weiss Laurence, Bouchaud Olivier, Felizarta Franco, Meurer Anja, Raffi François, Esser Stefan, Katlama Christine, Koletar Susan L, Mounzer Karam, Swindells Susan, Baxter John D, Sc: The F4/AS01B HIV-1 Vaccine Candidate Is Safe and Immunogenic, But Does Not Show Viral Efficacy in Antiretroviral Therapy-Naive, HIV-1-Infected Adults: A Randomized Controlled Trial. Medicine 95 (6): e2673,2016.

Beck JM, Schloss PD, Venkataraman A, Twigg IH, Jablonski KA, Bushman FD, Campbell TB, Charlson ES, Collman RG, Crothers K, Curtis JL, Drews KL, Flores SC, Fontenot AP, Foulkes MA, Frank I, Ghedin E, Huang L, Lynch SV, Morris A, Palmer BE, Schmidt TM, Sodergren E, Weinstock GM, Young VB, Lung HIV Microbiome Project: Multi-center Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals American journal of respiratory and critical care medicine 192 (11): 1335-44,2015.

Fuchs JD, Frank I, Elizaga ML, Allen M, Frahm N, Kochar N, Li S, Edupuganti S, Kalams SA, Tomaras GD, Sheets R, Pensiero M, Tremblay MA, Higgins TJ, Latham T, Egan MA, Clarke DaK, Eldridge JH, HVTN 090 Study Group and the National Institutes of Allergy and Infectious Diseases HIV Vaccine Trials Network, Mulligan M, Rouphael N, Estep S, Rybczyk K, Dunbar D, Buchbinder S, Wagner T, Isbell R, Chinnell V, Bae J, Escamilla G, Tseng J, Fair R, Ramirez S, Broder G, Briesemeister L, Ferrara A: First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090) Open forum infectious diseases 2 (3): ofv082,2015.

Koblin BA, Grant S, Frye V, Superak H, Sanchez B, Lucy D, Dunbar D, Graham P, Madenwald T, Escamilia G, Swann E, Morgan C, Novak RM, Frank I: HIV Sexual Risk and Syndemics among Women in Three Urban Areas in the United States: Analysis from HVTN 906 Journal of urban health : bulletin of the New York Academy of Medicine 92 (3): 572-83,2015.

Overton ET, Stapleton J, Frank I, Hassler S, Goepfert PA, Barker D, Wagner E, von Krempelhuber A, Virgin G, Meyer TP, Müller J, Bädeker N, Grünert R, Young P, Rösch S, Maclennan J, Arndtz-Wiedemann N, Chaplin P: Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial Open forum infectious diseases 2 (2): ofv040,2015.

Eberhart MG, Yehia BR, Hillier A, Voytek CD, Fiore DJ, Blank M, Frank I, Metzger DS, Brady KA: Individual and community factors associated with geographic clusters of poor HIV care retention and poor viral suppression Journal of acquired immune deficiency syndromes (1999) 69 Suppl 1 : S37-43,2015.

Hay CM, Wilson GJ, Elizaga M, Li S, Kochar N, Allen M, Sobieszczyk M, Frank I, Frahm N, Tomaras GD, Egan M, Pensiero M, Eldridge J: An HIV DNA Vaccine Delivered by Electroporation and Boosted by rVSV HIV-1 Gag Is Safe and Immunogenic in Healthy HIV-uninfected Adults AIDS research and human retroviruses 30 Suppl 1 : A17,2014.

Academic Contact Info

502 Johnson Pavilion
3610 Hamilton Walk 6073

Philadelphia, PA 19104-6073
Phone: 215-662-7419
Fax: 215-349-8011
Patient appointments: 800-789-7366 (PENN)

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