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CAR-T Cell Therapy: Using Healthy Cells to Fight Cancer

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What Is CAR-T Cell Immunotherapy?

How does the immune system fight cancer? It doesn't... without a boost.

The immune system relies on a powerful army of "T cells." They on are on the front line of our body's defenses. Their mission is to search and destroy anything that causes illness or infection. With cancer, the immune system often fails to deploy T cells right away or at all. When it does, the attack is ineffective.

Imagine a drug or therapy that could treat disease by helping the immune system do its job better. That was the idea in creating our CAR-T cell therapy, just one of the many immunotherapy treatment options available at Penn.

To learn how the CAR-T process works, view the infographic above and watch the video below.

Penn's FDA-Approved CAR-T Cell Therapy

With the discovery of the first gene therapy to be approved by the FDA, Penn Medicine is leading the world in immunotherapy research. Our researchers are working relentlessly to realize the full potential of this innovative approach: reprogramming the body’s own immune cells to seek and destroy every last cancer cell.

A personalized cellular therapy, our CAR-T cell therapy trains healthy cells to hunt down and eliminate cancer cells – making what was unthinkable yesterday into a reality today.

CAR-T cell therapy has become a powerful addition to Penn’s cancer-fighting arsenal of surgery, targeted therapies, and precision radiation treatments. We have treated nearly 500 blood cancer patients in CAR-T clinical trials.

See the impact that CAR-T therapy is having around the world: