Bone Marrow and Stem Cell Transplant Program

Today, there's more hope than ever for those who face a cancer diagnosis in which bone marrow or stem cell transplant is a treatment option. Our Bone Marrow and Stem Cell Transplant Program is one of the most established and largest in the country. By putting our experience to work, we offer the best possible treatment outcomes.

Backed by a premier bone marrow and stem cell transplant research program, we continue to make history in the development of new treatments through basic science research and clinical trials.

Types of Transplantation

  • A bone marrow transplant is a procedure to replace bone marrow that has been destroyed by treatment with high doses of anticancer drugs or radiation. Transplantation may be autologous (an individual's own marrow saved before treatment), allogeneic (marrow donated by someone else), or syngeneic (marrow donated by an identical twin).
  • A stem cell transplant is a method of replacing immature blood-forming cells that were destroyed by cancer treatment. The stem cells are given to the person after cancer treatment to help the bone marrow recover and continue producing healthy blood cells.
  • A bloodless stem cell transplant is an option for patients that prefer "no blood" methods of medical and surgical treatments. During a bloodless stem cell transplant, doctors remove some of your stem cells (which produce the body's blood cells) prior to high-dose chemotherapy. Once collected, these blood-forming cells are frozen until the high-dose chemotherapy is completed. Then the stem cells are re-infused into the patient. Learn more about bloodless medicine options at the Center for Transfusion-Free Medicine.
  • A cord blood transplant involves removing stem cells from a baby's umbilical cord immediately after birth and storing them for future use. Cord blood cells may be an alternative stem cell source for patients without a matched, unrelated donor.

Types of Diseases Treated with Bone Marrow and Stem Cell Transplant

Stem cell and bone marrow transplantation are procedures that may be recommended as a treatment for:

A Multidisciplinary Team of Experts

If bone marrow or stem cell transplant is a treatment option for you, it's important to have the best team of experts available.

Our Bone Marrow and Stem Cell Transplant Program is comprised of individuals who are nationally recognized for their expertise. They can provide the information, care, and support to help you each step of the way.

Our team offers:

  • Innovative clinical trials
  • A transplant facility approved by the National Marrow Donor Program
  • The backing of a major research program with immediate translation of findings to patient care
  • Multidisciplinary evaluation by physician specialists in medical oncology, surgical oncology, radiation oncology, radiology and pathology
  • Care provided by nurses, nurse practitioners, and physician assistants with advanced training and experience in bone marrow and stem cell transplant
  • Patient support specialists who are experts in navigating complex health care situations and act as a consistent point of contact and a reliable source for support
  • Cancer counselors who work exclusively with cancer patients and their families
  • Registered dietitians who specialize in cancer nutrition and provide information based on sound nutritional therapies

Shaping the Future of Cancer Care

Penn has one of the few Hematologic Malignancy Research Programs for the study of leukemia, lymphoma, and myeloma in the country that is approved and funded by the National Cancer Institute. It is through this research program that we have made significant advances in improving bone marrow and stem cell transplants.

The knowledge gained through our research allows us to better care for those undergoing bone marrow and stem cell transplants. Every day our scientists learn more about the causes of hematologic malignancies and discover better ways to prevent and detect them.