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Bone Marrow and Stem Cell Transplant Program

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Program Overview

The Abramson Cancer Center’s Bone Marrow and Stem Cell Transplant Program is one of the most established and largest in the country and offers a transplant facility approved by the National Marrow Donor Program.

If a bone marrow and stem cell transplant is a treatment option for you, our team of specialists in medical oncology, surgical oncology, radiation oncology, radiology, and pathology will provide thorough evaluations and develop a plan designed exclusively for you. Along the way, you’ll have exceptional care provided by nurses, nurse practitioners, physician assistants, and registered dietitians with advanced training and experience in bone marrow and stem cell transplant and cancer nutrition.

Our Bone Marrow and Stem Cell program also provides oncology navigators, who are experts in navigating complex health care situations and act as a consistent point of contact and a reliable source for support, as well as cancer counselors who work exclusively with you and your family.

Conditions Treated by Bone Marrow and Stem Cell Program

Stem cell and bone marrow transplantation are procedures that may be recommended as a treatment for:

Why Penn’s Bone Marrow and Stem Cell Transplant Program Is Different

Penn has one of the few hematologic malignancy research programs for the study of leukemia, lymphoma, and myeloma in the country that is approved and funded by the National Cancer Institute. It is through this research program that we have made significant advances in improving bone marrow and stem cell transplants.

Backed by this premier bone marrow and stem cell transplant research program, we continue to make history in the development of new treatments through basic science research and clinical trials.

The knowledge gained through our research allows us to better care for those undergoing bone marrow and stem cell transplants. Every day our scientists learn more about the causes of hematologic malignancies and discover better ways to prevent and detect them.

Treatments and Services Offered by the Bone Marrow and Stem Cell Program

A bone marrow transplant is a procedure to replace bone marrow that has been destroyed by treatment with high doses of anticancer drugs or radiation. Transplantation may be autologous (an individual's own marrow saved before treatment), allogeneic (marrow donated by someone else), or syngeneic (marrow donated by an identical twin).

A stem cell transplant is a method of replacing immature blood-forming cells that were destroyed by cancer treatment. The stem cells are given to the person after cancer treatment to help the bone marrow recover and continue producing healthy blood cells.

A bloodless stem cell transplant is an option for patients that prefer "no blood" methods of medical and surgical treatments. During a bloodless stem cell transplant, doctors remove some of your stem cells (which produce the body's blood cells) prior to high-dose chemotherapy. Once collected, these blood-forming cells are frozen until the high-dose chemotherapy is completed. Then the stem cells are re-infused into the patient. Learn more about bloodless medicine options at the Center for Transfusion-Free Medicine.

A cord blood transplant involves removing stem cells from a baby's umbilical cord immediately after birth and storing them for future use. Cord blood cells may be an alternative stem cell source for patients without a matched, unrelated donor.