Penn Medicine magazine

Discover extraordinary advances in medical science, transformations of health care, and the people driving change, in stories from the Perelman School of Medicine alumni magazine.
Nicholas Palmer, wearing a face shield and thick gloves, pours cold liquid nitrogen from a jug into a vessel with a snowflake symbol in a coolly lit lab

Freeze, image, cure

Researchers are capturing images of the biology inside our cells using cryogenic electron microscopy to inform how we understand and treat disease.

Pam Fisher, left, and Kara Buda, PhD, right, stand outside talking

Cancer care for the mind and spirit

A program where cancer patients can get free mental health care addresses an underrecognized need: that cancer’s deepest wounds are often not physical.

Latest articles

How cryoEM creates new views of life and medicine

Benjamin Creekmore looks into the eyepiece of a microscope

Seeing the mechanisms of disease with cryoEM

Understanding how a disease starts and gets going is essential to finding treatments—and imaging with cryoEM and cryoET is leading to such insights.

  • Catherine Zandonella
  • February 9, 2026
Vera Moiseenkova-Bell, PhD, with a large physical model of an ion channel protein complex

Zooming into drug discovery with cryo-microscopic science

Penn is at the forefront of using close-up imaging techniques to suggest new ways to match drugs to biological receptors like a key with a lock.

  • Catherine Zandonella
  • February 9, 2026
Standing next to a microscope, Kathryn Kixmoeller pours liquid nitrogen from a jug into a small sample container

Biological insights of the future come from cryoEM today

Structural biologists are now more clearly seeing fundamental mechanisms of how cells function in the human body and across many forms of life.

  • Catherine Zandonella
  • February 9, 2026

Innovations in medical education 

A Perelman School of Medicine classroom

On a mission to transform medical education

From precision education to AI, two new leaders are exploring innovative ways to train tomorrow’s doctors.

  • Nicole Sweeney Etter
  • December 3, 2025
An illustration of medical students in short white coats standing confidently, connected to illustrated bubbles showing patient interactions and a tablet

Can AI tools help train a more effective physician?

Penn Medicine is leveraging emerging technology to strengthen clinical reasoning skills and patient care among medical students and residents.

  • Nicole Sweeney Etter
  • January 13, 2026
Kevin Mahoney, Jennifer Kogan, J. Larry Jameson, Rod Wong, Marti Wong, Lisa Bellini, and Jonathan Epstein at a Perelman School of Medicine donation event

Penn Medicine to redesign physician training with landmark gift

The gift sparks curriculum transformation, new lectureship, and names Entrepreneurship Pathway in honor of alumnus Rod Wong, M03.

  • January 22, 2026

The human dimension of health care

Deborah Burnham has led the Writing a Life group since 2015

She helps patients find their words to cast a spell on cancer

Even before she experienced cancer herself, Deborah Burnham, PhD, had a knack for “magical” prompts to help cancer patients write through their illness.

  • Daphne Sashin
  • February 4, 2026
Colorful coffee mugs on a round table, each printed with words like Essential, Timeless, and Trailblazing

One of the first, still foremost: Penn Bioethics marks 30 years

Three decades of training leaders and driving research that defines ethics in health care, policy, and innovation were honored with a national award.

  • Carmen Lennon
  • November 21, 2025
diagram labeled for Whole Person Care Collaborative

Addressing ‘whole person care’ as part of cancer treatment

The Abramson Cancer Center’s legacy of holistic care is the foundation for cancer care and research that aims to become a model for the world.

  • February 2, 2026

At the forefront of medical discoveries past, present, and future

A view of a photographic glass plate showing a coin purse with two coins inside. Two gloved hands hold open the cardboard housing the glass.

X-ray plates from 1896 give a snapshot of Penn’s place in history

A pair of early X-ray plates represent the beginning of a revolution in medicine that began at Penn.

  • Daphne Sashin
  • October 6, 2025
Bennett looking into a microscope and a researcher using a pipette at a lab bench

Transformative times, transformative leaders: an oral history

Penn Medicine’s eminence today traces back to decades-ago investments in people, places, and uniting in the purpose of academic medicine.

  • Rachel Ewing
  • November 17, 2025
A hand holding a trophy against a grey background.

Four Penn studies named among nation’s top clinical research advances

Perelman School of Medicine papers win Clinical Research Forum’s 2026 Top 10 Clinical Research Achievement Awards, highlighting the power of federal funding for science.

  • January 20, 2026

People of Penn Medicine

Florencia Polite speaking with a pregnant patient

Healer, educator, advocate: Meet Dr. Florencia Polite

At home and overseas, Florencia Polite, MD, is on a mission to help patients and physicians understand how RSV vaccines protect newborns.

  • Meredith Mann
  • November 12, 2025
Two medical students sorting through a pile of clothes with a bearded man wearing a hat and an orange and black shirt

Penn’s future doctors build trust on the streets

Penn medical students are forging connections with those experiencing homelessness and shining a light on the transformative power of street medicine.

  • Daphne Sashin
  • October 6, 2025
Donita Brady smiling on a campus with buildings and a tree-lined path in the background.

Maximizing access to science with Donita Brady, PhD

The 2026 recipient of the ASBMB Ruth Kirschstein Award for Maximizing Access in Science shares her approach to creating opportunities for all.

  • Meagan Raeke
  • September 22, 2025

Breathtaking biomedical advances

Luka Krizanac in June 2025

With the gift of hands comes feeling like ‘a whole human’

Getting Luka Krizanac new hands took 16 years, a connection between a surgeon and his mentor, and surgeries on two continents.

  • Daphne Sashin
  • June 13, 2025
Eduart Cuka, sitting up proud and happy in an infusion chair, with Stephen Bagley, MD, at his side, looking at him

How discoveries become cures, in a virtuous cycle

Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures.

  • Nicole Sweeney Etter and Rachel Ewing
  • July 10, 2025
Kiran Musunuru and Rebecca Ahrens-Nicklas

World’s first patient treated with personalized CRISPR therapy

In a historic medical breakthrough, a child with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy.

  • May 15, 2025

Getting patients to the right care in the right place

Pilot Eric Houghton inspects a PennSTAR helicopter on the rooftop of the Clifton Center for Health Care Innovation at the Hospital of the University of Pennsylvania with the skyline of Philadelphia in the background

PennSTAR delivers critical care in the air, across the region

For PennSTAR, Penn Medicine’s critical care transport service, any given day brings a new opportunity to save lives—at high speed and altitude, anywhere they’re needed across the region.

  • Kris Ankarlo
  • January 15, 2026
A line illustration of house- and hospital-shaped buildings is overlaid with large map location pin markers on a colorful background

Right place, right care

Penn Medicine is building better systems that help patients build health care around their lives instead of their lives around health care.

  • Kris Ankarlo
  • October 14, 2025
Robin Wood and William Schweickert converse while sitting in an office filled with cubicles

Hospital capacity management teams are making space for miracles

Behind the scenes, it takes smart capacity management systems to serve patients who need nothing less than the most advanced health care available anywhere.

  • Christina Hernandez Sherwood
  • October 10, 2025

Development matters

Exterior of 3600 Civic Center Boulevard facility.

Ushering in a bold new era of Immune Health discovery

A reimagined facility has been introduced as the epicenter for pioneering Penn research aimed at “breaking the immunological code” of autoimmune diseases and bringing them to heel.

  • September 5, 2025
CHOP, Penn Medicine, the Lurie Family, City of Philadelphia, and Commonwealth of Pennsylvania leaders below a sign of the Lurie Autism Institute logo

Penn, CHOP launch Lurie Autism Institute with $50 million gift

A $50 million gift from the Lurie family to Children’s Hospital of Philadelphia and Penn Medicine will launch the Lurie Autism Institute to drive autism research.

  • June 10, 2025
Group photo of Dhan Pai, J. Larry Jameson, Catherine and Anthony Clifton, Regina Cunningham, Kevin B. Mahoney, and Jonathan A. Epstein

A transformational gift to accelerate Penn Medicine care

The Pavilion will be renamed to recognize Catherine and Anthony Clifton’s historic philanthropic commitment that will usher in a new era of innovation.

  • February 12, 2025

Stopping cancer at every step

Illeana Casiano-Vazquez, smiling and relaxed at home

Keeping cancer conquered

Penn Medicine research is bringing the “sleeper” phase of cancer to light—creating hope that more cancers could be wiped out for good and never come back.

  • Kirsten Weir
  • May 20, 2025
An illustration of a cross-section of bone marrow cells, including some ominous brown cells representing dormant tumor cells

Sleeper cells: the science of cancer dormancy

Penn researchers have spent decades detecting where tumor cells lurk after treatment in hopes of finding them in time to stop cancer from coming back.

  • Kirsten Weir
  • May 20, 2025
Maggie Gaines as a young woman with her mother, relaxed near water

Volunteering for cancer research: an act of love

The Basser Center for BRCA is running an innovative cancer interception clinical trial that depends on volunteers with deep, personal ties to cancer.

  • Meagan Raeke
  • May 20, 2025

The reimagineers transforming health care

Illustration of human figures in a retro-futuristic landscape of ideas in bubbles with text “The Reimagineers”

The reimagineers of Penn Medicine

Penn Medicine is harnessing technology, innovation, and physician insights to make health care easier for clinicians and patients.

  • Christina Hernandez Sherwood
  • April 4, 2025
Portrait photo of Mitchell Schnall

The tinkerer-turned-tech leader

Mitchell Schnall, MD, PhD, is using his insights from technology in radiology to solve problems and scale up changes in the health system.

  • Christina Hernandez Sherwood
  • April 4, 2025
Portrait photo of Raina Merchant 

The connected, creative innovator

Nearly two decades into her tenure at Penn, Raina Merchant, MD, leads teams transforming health care for better patient, clinician, and community experiences.

  • Christina Hernandez Sherwood
  • April 4, 2025

With greenery and justice for all

A young Black man in sunglasses leans over a raised garden bed with strawberry plants, with a city rowhouse scene in the distance behind him

Health, greenery, and justice for all

Reversing racial inequities is a full-force effort rooted in research that includes gardens and parks, financial support, and lifting up local community members.

  • Christina Hernandez Sherwood
  • November 11, 2024
Portrait of Eugenia South and Atheendar Venkataramani standing together in a green space

A large-scale research study of health, wealth, and greening

Combining economic assistance with greening initiatives in a randomized trial, IGNITE aims to show how to reverse the harms of racial injustice in health.

  • Christina Hernandez Sherwood
  • November 11, 2024
In an urban park with mature trees, people gather under pop-up tents

‘We are all Deeply Rooted’

Deeply Rooted is a community partnership that plants trees, greens vacant lots, and funds grassroots programs. The goal: health justice in action.

  • Christina Hernandez Sherwood
  • November 11, 2024

Penn Medicine goes green

An illustration with a texture like recycled paper shows colorful green hills, solar panels, and a hospital building and city skyline

How Penn Medicine is going green for good health

To improve health while addressing climate change, Penn Medicine aims to become the most environmentally friendly health care system in the country.

  • Christina Hernandez Sherwood
  • March 29, 2024
Caoimhe Duffy, Julia Tchou, and Matt Carey stand outside of an operating room

Penn teams address climate impacts in the operating room

From rethinking anesthesia gases that have outsized greenhouse effects, to medical waste disposal, Penn Medicine is reducing the climate impacts of surgery.

  • Christina Hernandez Sherwood
  • March 29, 2024
An illustration of the sun’s rays hitting the earth and bouncing off of the earth and atmosphere to depict global warming 

Health research on a warming planet

Climate change affects health, from viral transmission to the effectiveness of medications. Penn researchers are discovering how and seeking solutions.

  • Christina Hernandez Sherwood
  • March 29, 2024

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