News Release
Danielle Sandsmark, MD, PhD & Dennis Kolson, MD, PhD

PHILADELPHIA—According to a recent study, as many as one in three COVID-19 survivors experience a mental health or neurological disorder within six months of a coronavirus infection, adding to a growing body of evidence that show COVID-19 can have serious and potentially long-lasting effects on the brain.

The Penn Neuro COVID Clinic aims to assess and treat long-haul COVID patients suffering from neurological symptoms. Recently launched by the Department of Neurology at the University of Pennsylvania’s Perelman School of Medicine, the clinic focuses on patients who previously tested positive for COVID-19 and experience symptoms related to cognition, headache, vertigo, and brain fog. This is the first such clinic in the region.

“We are still learning about impact of the virus on our bodies, but the Penn Neuro COVID Clinic allows physicians to implement proper outpatient services to patients experiencing the neurological aspects of long-haul COVID,” says Frances Jensen, MD, FACP, chair of Neurology. “It is also our goal to establish standardized evaluation and treatment protocols, and ultimately develop clinical trials to expand our understanding and treatment of patients affected by the virus.”

Sara Manning Peskin, MD, MS & Matthew Schindler, MD, PhD

The clinic offers standardized cognitive tests to evaluate symptoms and diagnose patients, as well as screens for mental health disorders also associated with COVID-19, such as depression and anxiety. The clinic can offer referrals to the appropriate providers within the Penn Medicine network of physical, occupational, cognitive therapists, and physician subspecialists based on individual needs.

“We know how frustrating it is for long-haul COVID patients who are experiencing these symptoms,” says Danielle Sandsmark, MD, PhD, an assistant professor of Neurology, one of four physicians leading the clinic. “First and foremost, we want our patients to feel heard, and then we want to administer excellent care to manage symptoms and provide relief.”

Additional physicians at the Penn Neuro COVID Clinic include Dennis Kolson, MD, PhD, a professor of Neurology, Sara Manning Peskin, MD, MS, an assistant professor of Neurology, and Matthew Schindler, MD, PhD, an instructor of Neurology. With backgrounds in different aspects of neurology – including cognitive neurology, neuroimaging, neurovirology and immunology, and neurocritical care – the physicians combine their varied expertise to give 360-degree evaluation and care to patients.

“COVID-19 is here to stay at some prevalence,” says Kolson. “In addition to treating patients currently suffering the long-term symptoms, our goals at the clinic are to also understand not only the neurological complications and pathogenic mechanisms of the infection, but also to develop treatments to mitigate the future negative effects on patients.”

The Penn Neuro COVID Clinic is conducting visits both in-person and virtually. All neurological patients are currently being referred through Penn Medicine’s Physical Medicine & Rehabilitation Post-COVID Assessment and Recovery Clinic, which can be reached by calling 215-893-2668.

Penn Medicine is one of the world’s leading academic medical centers, dedicated to the related missions of medical education, biomedical research, excellence in patient care, and community service. The organization consists of the University of Pennsylvania Health System and Penn’s Raymond and Ruth Perelman School of Medicine, founded in 1765 as the nation’s first medical school.

The Perelman School of Medicine is consistently among the nation's top recipients of funding from the National Institutes of Health, with $550 million awarded in the 2022 fiscal year. Home to a proud history of “firsts” in medicine, Penn Medicine teams have pioneered discoveries and innovations that have shaped modern medicine, including recent breakthroughs such as CAR T cell therapy for cancer and the mRNA technology used in COVID-19 vaccines.

The University of Pennsylvania Health System’s patient care facilities stretch from the Susquehanna River in Pennsylvania to the New Jersey shore. These include the Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, Chester County Hospital, Lancaster General Health, Penn Medicine Princeton Health, and Pennsylvania Hospital—the nation’s first hospital, founded in 1751. Additional facilities and enterprises include Good Shepherd Penn Partners, Penn Medicine at Home, Lancaster Behavioral Health Hospital, and Princeton House Behavioral Health, among others.

Penn Medicine is an $11.1 billion enterprise powered by more than 49,000 talented faculty and staff.

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