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CRISPR “Minigene” Approach Stops Genetic Liver Disease in Mice

A new CRISPR gene-editing technique prevented a genetic liver disease known to be driven by hundreds of different mutations and improved clinical symptoms in mice, Penn Medicine researchers reported in new proof-of-concept study published online in Science Advances.

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Penn Medicine In the News

  • ‘Ditch the Disk’ Group of Tech Execs Is Spurring the Medical Industry to Move on from CD-ROMs

    February 16, 2020
  • With Viruses Like Flu and Coronavirus, Pneumonia Often Delivers the Fatal Blow

    February 14, 2020
  • Carl June on CRISPR, CAR T, and How the Vietnam War Dropped Him Into Medicine

    February 14, 2020
  • Stalling Need for ADT in Recurrent Prostate Cancer

    February 14, 2020
  • Penn Study Suggests Editing Human Genes to Fight Cancer is Safe

    February 12, 2020
  • Streamline Development Sued for Defective Building

    January 31, 2020
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