Landmark Kidney Study at Penn
Seeks Volunteers

Project Aims to Discover how Kidney Disease Affects the Heart

(Philadelphia, PA) – Researchers at the Hospital of the University of Pennsylvania are looking for volunteers to participate in the Chronic Renal Insufficiency Cohort (CRIC) study. The landmark project is being led by Raymond Townsend, MD, Associate Professor of Medicine. The multi-site, national study will try to gain a better understanding of kidney (renal) problems and their effects on the heart.

Volunteers should be 21 to 74 years old with modest impairment of kidney function (this is measured by a blood test called the ‘serum creatinine’ level), but not on dialysis, and must not have undergone a kidney transplant. Researchers will carefully monitor participants’ heart and kidney health for several years through an annual visit, which includes a physical exam, echocardiograms after 1 and 4 years, blood tests, and urine samples. Volunteers and their doctors will be provided with study results. All tests are free of charge and there is modest compensation for participants’ involvement.

Researchers hope to recruit 3000 participants in the USA, with about 450 coming from Pennsylvania, New Jersey and Delaware. Completion of enrollment for the study is expected to take two years, finishing in December 2005, with subjects followed-up for 4 years. The study is sponsored by the National Institutes of Health (NIH), through the branch of the NIH known as the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK).

Anyone interested should call (215) 662-3636 or (215) 662-2962. The toll free number is 1-866-589-CRIC (2742). More information about the CRIC study can be obtained through the internet by going to or by contacting the research team through an email at

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PENN Medicine is a $2.5 billion enterprise dedicated to the related missions of medical education, biomedical research, and high-quality patient care. PENN Medicine consists of the University of Pennsylvania School of Medicine (founded in 1765 as the nation’s first medical school) and the University of Pennsylvania Health System (created in 1993 as the nation’s first integrated academic health system).

Penn’s School of Medicine is ranked #2 in the nation for receipt of NIH research funds; and ranked #4 in the nation in U.S. News & World Report’s most recent ranking of top research-oriented medical schools. Supporting 1,400 fulltime faculty and 700 students, the School of Medicine is recognized worldwide for its superior education and training of the next generation of physician-scientists and leaders of academic medicine.

Penn Health System consists of four hospitals (including its flagship Hospital of the University of Pennsylvania, consistently rated one of the nation’s “Honor Roll” hospitals by U.S. News & World Report), a faculty practice plan, a primary-care provider network, three multispecialty satellite facilities, and home health care and hospice.

Penn Medicine is one of the world’s leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $7.8 billion enterprise.

The Perelman School of Medicine has been ranked among the top five medical schools in the United States for the past 20 years, according to U.S. News & World Report’s survey of research-oriented medical schools. The School is consistently among the nation’s top recipients of funding from the National Institutes of Health, with $405 million awarded in the 2017 fiscal year.

The University of Pennsylvania Health System’s patient care facilities include: The Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center — which are recognized as one of the nation’s top “Honor Roll” hospitals by U.S. News & World Report — Chester County Hospital; Lancaster General Health; Penn Medicine Princeton Health; Penn Wissahickon Hospice; and Pennsylvania Hospital – the nation’s first hospital, founded in 1751. Additional affiliated inpatient care facilities and services throughout the Philadelphia region include Good Shepherd Penn Partners, a partnership between Good Shepherd Rehabilitation Network and Penn Medicine, and Princeton House Behavioral Health, a leading provider of highly skilled and compassionate behavioral healthcare.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2017, Penn Medicine provided $500 million to benefit our community.

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