The Penn Sjögren's Syndrome Center, part of Penn Rheumatology, provides a multidisciplinary approach to treating patients with Sjögren's syndrome. It is the only major treatment center for Sjögren's within a 100-mile radius of Philadelphia, treating patients from across the country and around the world. Services are provided by a network of Penn Medicine specialists who are experts in treating various Sjögren's-related problems.

Based at Penn Medicine University City, Penn's Sjögren's Syndrome Center serves as the regional headquarters of the Philadelphia Chapter of the Sjögren's Syndrome Foundation.

Symptoms of Sjögren's Syndrome

While some patients experience mild discomfort from their symptoms, others suffer debilitating symptoms that greatly impair their quality of life. Patients may also experience exocrine gland dysfunction in other organs. In about 25 percent of cases, the disease may spread to the internal organs and cause arthritis, fatigue or problems of the lungs, kidneys and central nervous system. In 4-5 percent of cases, Sjogren's may also be complicated by lymphomas.

Sometimes, Sjögren's may present with symptoms other than dry eyes and dry mouth, and in some cases, the symptoms of dry eyes and dry mouth may be completely absent.

Sjögren's Syndrome Diagnosis and Treatment

Rheumatologists at the Penn Sjögren's Syndrome Center collaborate closely with specialists in ophthalmology, oral medicine and ENT to provide a complete diagnosis and treatment program for patients suffering from Sjögren's.

If Sjögren's is suspected, a series of physical exams, blood tests, ophthalmologic tests and dental tests are used to confirm the diagnosis. The course of treatment may include prescription medications, over-the-counter products and non-medical therapy. Treatment includes eye care at the Penn Dry Eye and Ocular Surface Center of the Scheie Eye Institute of the University of Pennsylvania, mouth care from Penn Oral Medicine and salivary gland care from Penn ENT's Salivary Gland Center.

In This Section

Treatment Team

Penn rheumatologists use a multidisciplinary approach and create personalized treatment plans for those with Sjögren's syndrome.

Sjögren's Resources

Adjusting your diet, understanding how to manage symptoms and attending support groups can improve the quality of life for those with Sjögren's syndrome.

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