Allergy and immunology

Allergies, asthma, and immune conditions can affect how you feel every day. At Penn Medicine, our allergy and immunology specialists diagnose and treat both common and complex disorders, including conditions not commonly managed at other centers.
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Comprehensive allergy and immunology care

At Penn Medicine, you receive care from specialists who focus exclusively on allergy, asthma, immune system disorders, and symptoms like chronic cough. As a World Allergy Organization Center of Excellence, we’re recognized globally for our leadership in research and patient care. This designation means you have access to innovative therapies, diagnostic tools, and clinical trials not widely available elsewhere.

Your care is tailored to your specific needs and may include:

  • Immunotherapy: Allergy shots and venom immunotherapy help reduce sensitivity to allergens, including stinging insect allergies.
  • Asthma treatment: Inhalers, medications, and breathing strategies to help control symptoms and reduce asthma attacks.
  • Biologic therapies: These medications help manage severe allergies and asthma by targeting specific immune system pathways.
  • Drug allergy evaluation: Testing and monitored challenges help identify true drug allergies and reduce the risk of future reactions.
  • Immune support: Immunoglobulin therapy helps people with immune deficiencies fight infections and stay healthier.

Clinical trials

Clinical trials offer patients the opportunity to try new and effective treatments and take part in future research.

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Second opinions

If you've received a diagnosis, our team of experts offers second opinions to grant you peace of mind.

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Advanced options for drug allergies and asthma

At Penn Medicine, our allergy immunologists offer you access to programs and treatments that are not commonly found elsewhere. This includes access to innovative treatment options for drug allergies and hard-to-control asthma. 

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Drug Allergy Program

Research shows that more than 90 percent of people with a penicillin or amoxicillin allergy label can safely take these medications. Our allergy specialists work to clear these drug allergy labels. Our team uses your medical history, skin testing, and monitored drug challenges to see how you react in a safe, controlled setting. We evaluate allergies to antibiotics, other medications, and numbing agents (anesthesia). We also provide specialized care for pregnant patients who may need certain antibiotics during pregnancy, labor, and delivery.
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The Penn Asthma Program

Asthma that is hard to control can lead to frequent flares, emergency visits, and missed days from work or school. The asthma allergy care team at Penn Medicine includes experts in both allergy and pulmonology who work closely with other specialists to deliver coordinated care. We use advanced diagnostics to find your specific triggers and create a custom treatment plan. Once a diagnosis is made, we offer innovative therapies, including targeted treatments and access to clinical trials. Our program is also deeply committed to reducing disparities in asthma care and improving outcomes for underserved communities.
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Conditions we treat

  • Allergic rhinitis
  • Angioedema
  • Asthma
  • Drug allergies
  • Eosinophilic esophagitis
  • Food allergy
  • Hives
  • Immunodeficiency diseases
  • Insect bites and stings
  • Sinus infection (sinusitis)
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Our doctors

Our providers work with you to plan and deliver exceptional treatment and personalized care.

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Locations

Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.

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