Infectious disease care

Harmful bacteria, viruses, fungi, and parasites can cause serious illnesses. At Penn Medicine, our infectious disease specialists provide compassionate care focused on prevention, diagnosis, and effective treatment for a range of diseases.
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Expert care for all types of infectious diseases

Our infectious disease providers are highly specialized in illnesses that can spread through germs, from staph infections to viral hepatitis. We work with you on strategies to prevent infectious diseases whenever possible and provide diagnostic tests and advanced treatments when infections do occur. Your care is always handled with compassion and is tailored to meet your specific needs.

Specialties and treatments

HIV care
Our affirming, trusted HIV care includes the most advanced prevention medications and HIV treatments.
Mycobacterial Infection Clinic
We specialize in diagnosing and treating complex lung and mycobacterial infections.
Infectious Diseases Transplant Clinic
We provide effective infection prevention and care before and after transplant.
Skin and soft tissue infection care
Penn Medicine specialists provide expert care for skin and soft tissue infections (SSTI) like MRSA.
Viral hepatitis care
Our skilled infectious disease specialists blend expertise and compassion when treating viral hepatitis.
Sexual health and preventative care
We specialize in sexual health services, including STI testing, treatment, and prevention.

Clinical trials

Clinical trials offer patients the opportunity to try new and effective treatments and take part in future research.

Find a clinical trial

Second opinions

If you've received a diagnosis, our team of experts offers second opinions to grant you peace of mind.

Schedule a second opinion

Conditions we treat

  • Coronavirus (COVID-19)
  • Flu (influenza)
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Human immunodeficiency virus (HIV)
  • Lyme disease
  • Measles
  • Meningitis
  • Pulmonary tuberculosis
  • Sepsis
  • Viral pneumonia

Advancing infectious disease health through research

In addition to exceptional clinical care, we drive progress in infectious disease control and treatment through clinical trials and other research. Penn investigators are part of a wide array of innovative research programs that advance knowledge and foster a culture of excellence in the treatment of infectious diseases. We have made considerable strides in HIV research by mapping out immune cells to yield the world’s first comprehensive B-cell clone atlas, which is helping propel the study of future therapies. As one of the world’s leading academic medical centers, we drive innovation in infectious disease medicine and communicable diseases.

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Travel medicine services

We connect you with travel medicine and tropical disease specialists who can provide needed vaccines and review prevention strategies specific to your destination. If you return with an illness, our treatments can get you back to feeling better. 

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Our doctors

Our providers work with you to plan and deliver exceptional treatment and personalized care.

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Locations

Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.

Related articles

An immune system for a city

A decentralized approach modeled on the immune system detected more disease-carrying insects than conventional surveillance in Peru.

  • August 5, 2026

‘Nudging’ boosts flu vaccine numbers

When patients got text messages from their primary care practice, and the providers were nudged themselves to boost vaccination numbers, rates jumped.

  • January 27, 2026

Rabies in Peru highlights global threats of health inequity

A Penn Medicine-led analysis showed that surveillance of dog rabies in Arequipa, Peru, was lacking in areas with lower socioeconomic status and could spell problems for infectious disease worldwide.

  • November 5, 2025

Future mRNA vaccines may prevent food and seasonal allergies

A new Penn mRNA vaccine stopped allergens from causing dangerous immune reactions and life-threatening inflammation in mice.

  • September 26, 2025

Patient stories

A miracle recovery to see his kids graduate

A miracle recovery to see his kids graduate

After falling severely ill with COVID-19 in the fall of 2020, Fred Rahmanian became the first COVID-19 lung transplant patient in Pennsylvania. “This whole thing has been a miracle. Everyone knew I was at the end of the line. There was no expectation that I would live until Penn stepped in.”

A quick response to a dangerous infection

A quick response to a dangerous infection

“I can’t say enough about Dr. Jammalamadaka and everyone at my primary care practice,” said Dennis Rodkey. “Now, I have connections to other specialists and resources. They keep in touch with me and know what’s going on with my health. Whenever I have a question, they answer right away and nothing is ever a problem.”

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Schedule an appointment

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