Division of Pulmonary, Allergy and Critical Care

Thoracic oncology conducts cutting-edge diagnostic and therapeutic research related to lung cancer and malignant mesothelioma.

Faculty members in Penn Medicine's pulmonary division, led by Steven Albelda, MD, interact closely with faculty from thoracic surgery, oncology and pathology.

Other members of the group include Drs. Anil Vachani, Andrew Haas, Melpo Christofidou-Solomidou, and Edmund Moon from Pulmonary, Drs. Sunil Singhal and Evgeniy Eruslavnov from Thoracic Surgery, Dr. Corey Langer from Oncology, and Drs. Leslie Litzky and Charu Desponde from pathology. Research from this group is supported by NCI-funded Program Projects, a NIEHS Superfund Grant, NIH RO1 and KO8 grants, Industry, and Foundation support. The Abramson Cancer Center supports a Translational Center of Excellence in Lung Cancer Immunobiology and Immunotherapy.

Members of the group and their research interests include:

  • Steve Albelda, MD
    • Preclinical studies of immunogene therapy for lung cancer and mesothelioma
    • Immune analysis of clinical trials using gene therapy or immunotherapy
    • Understanding the lung cancer tumor microenvironment
    • Precision Medicine
    • Optimizing adoptive T cell transfer for the treatment of thoracic malignancies
  • Melpo Christofidou-Solomidou, PhD
    • Chemoprevention of lung carcinogenesis and evaluation of anti-carcinogenic effects of common botanicals
  • Andrew Haas, MD, PhD
    • Clinical trials using gene therapy or immunotherapy to treat malignant mesothelioma and lung cancer
    • Interventional bronchoscopy treatment of COPD
  • Edmund Moon, MD
    • Augmenting Adoptive T cell transfer
    • Immunobiology of T cell hypofunction
  • Sunil Singhal, MD / Evgeniy Eruslanov, PhD
    • Intraoperative imaging to detect residual or recurrent cancer
    • Lung cancer microenvironment with a focus on myeloid cells
  • Anil Vachani, MD
    • Determination of markers to predict survival after lung cancer surgery
    • Discovery of biomarkers for early detection of lung cancer
    • Gene environment interactions in lung cancer
    • Precision Medicine
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