Penn AERD Center

Specialists at Penn Medicine’s nationally recognized AERD Center use research-driven therapies to provide lasting relief for aspirin-exacerbated respiratory disease. We’re the only multispecialty center in PA and NJ solely dedicated to treating this condition.

Young man coughing, suffering from chest pain from chronic disease

Regional access to nationally acclaimed AERD care

AERD and its accompanying symptoms can be difficult to manage standard treatments. Some people live for years with asthma, nasal polyps, and chronic sinus infections that get worse when they take aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).

The Penn AERD Center is recognized nationally as a unique multispecialty program. We’re the only center in the region that provides the gold standard of care for AERD, which includes sinus surgery, aspirin desensitization, and long-term aspirin therapy. With decades of experience, our experts have helped thousands of people with this condition to breathe easier and live with fewer symptoms, even if other methods haven’t been successful.

Multiple specialties, one unified team

At the Penn AERD Center, you’ll receive coordinated medical and surgical care from a skilled team of the country’s leading AERD specialists. Our medical director, John V. Bosso, M.D., is one of the nation’s most experienced providers in aspirin desensitization therapy. We also have highly skilled sinus surgeons who perform hundreds of AERD surgeries a year, and other ear, nose, and throat (ENT) specialists who provide care for AERD.

Our comprehensive AERD treatment can dramatically improve your symptoms. You can benefit from:

  • Less nasal congestion and reduced asthma attacks
  • Delayed regrowth of nasal polyps and fewer sinus surgeries
  • An improved sense of smell 
  • The need for fewer medications to manage AERD symptoms
  • Increased tolerance to NSAIDs

How one patient found answers at the Penn AERD Center

After 20 years of AERD symptoms, our life-changing treatment allowed Susan to breathe better and safely take NSAIDs again

Conditions we treat

Navigating AERD treatment at Penn Medicine

You don’t have to settle for short-term solutions for your AERD symptoms. Find lasting relief in our specialized therapies that address the underlying cause of the disease.

Our approach to AERD treatment

Driving discovery for the future of AERD care

Penn Medicine’s research on AERD makes us uniquely positioned to provide this innovative treatment. Learn about the contributions we’ve made to AERD advancements that make us leaders in our field.

AERD research and innovation at Penn Medicine

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