Ruth & Raymond Perelman Center for Advanced Medicine

Address: 3400 Civic Center Boulevard, Philadelphia, PA 19104

  • From Northeastern Areas
    From I-95 South, take the Vine Street/Center City Exit, stay left to 676 West (Vine Street Expressway). Follow 676 West to the I-76 East Exit 1, International Airport. Follow I-76 East (Schuylkill Expressway) to Exit 346A, South Street (left exit), and turn right on South Street. Make a left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
  • From the West & Montgomery County
    Take the Pennsylvania Turnpike to Exit 326, Valley Forge. Take I-76 East (Schuylkill Expressway) approximately 17 miles to Exit 346A, South Street (left exit), and turn right on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
  • From the North
    FROM THE NORTH Take I-476 (Northeast Extension) South to Exit 20, Mid-County. Pay the toll and continue south on I-476 to Exit 16A, I-76 East. Follow I-76 East (Schuylkill Expressway) approximately 17 miles to Exit 346A, South Street (left exit), and turn right on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
  • From the South / Philadelphia International Airport
    Take I-95 North to Exit 13, PA-291 toward I-76 West/Valley Forge (Schuylkill Expressway). Merge right. Cross Girard Point Bridge and turn left at light on 26th Street. Merge on I-76 West to Exit 346A, South Street (left exit), and turn left on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
  • From New Jersey
    Take I-295 to the Walt Whitman Bridge. Follow signs for I-76 West (Schuylkill Expressway) and take Exit 346A, South Street (left). Turn left on South Street and turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
    • Alternate Route from New Jersey and points East
      Take the New Jersey Turnpike to Exit 3. Follow the Black Horse Pike (Route 168 North) for one mile to I-295 South. Go one mile to Exit 26 for I-76 West to the Walt Whitman Bridge. Cross the Bridge to take I-76 West (Schuylkill Expressway) to Exit 346A, South Street (left exit), and turn left on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.

Hospital of the University of Pennsylvania campus map

Download campus map with traffic patterns, driving directions and parking information (PDF).

From Philadelphia International Airport (PIA)

  • Driving: All major car rental companies are located at the airport.

  • Airport Train: The train leaves every half hour at 10 minutes and 40 minutes past the hour, and it arrives at University City Station on the HUP campus. The train costs approximately $5 and takes 20 minutes.

  • Taxi: A metered cab from the airport costs approximately $20 and the ride takes approximately 20 minutes.

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