Address: 3400 Civic Center Boulevard, Philadelphia, PA 19104
- From Northeastern Areas
From I-95 South, take the Vine Street/Center City Exit, stay left to 676 West (Vine Street Expressway). Follow 676 West to the I-76 East Exit 1, International Airport. Follow I-76 East (Schuylkill Expressway) to Exit 346A, South Street (left exit), and turn right on South Street. Make a left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
- From the West & Montgomery County
Take the Pennsylvania Turnpike to Exit 326, Valley Forge. Take I-76 East (Schuylkill Expressway) approximately 17 miles to Exit 346A, South Street (left exit), and turn right on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
- From the North
FROM THE NORTH Take I-476 (Northeast Extension) South to Exit 20, Mid-County. Pay the toll and continue south on I-476 to Exit 16A, I-76 East. Follow I-76 East (Schuylkill Expressway) approximately 17 miles to Exit 346A, South Street (left exit), and turn right on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
- From the South / Philadelphia International Airport
Take I-95 North to Exit 13, PA-291 toward I-76 West/Valley Forge (Schuylkill Expressway). Merge right. Cross Girard Point Bridge and turn left at light on 26th Street. Merge on I-76 West to Exit 346A, South Street (left exit), and turn left on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
- From New Jersey
Take I-295 to the Walt Whitman Bridge. Follow signs for I-76 West (Schuylkill Expressway) and take Exit 346A, South Street (left). Turn left on South Street and turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
- Alternate Route from New Jersey and points East
Take the New Jersey Turnpike to Exit 3. Follow the Black Horse Pike (Route 168 North) for one mile to I-295 South. Go one mile to Exit 26 for I-76 West to the Walt Whitman Bridge. Cross the Bridge to take I-76 West (Schuylkill Expressway) to Exit 346A, South Street (left exit), and turn left on South Street. Turn left on 34th Street. The Perelman Center for Advanced Medicine is on the left.
Download campus map with traffic patterns, driving directions and parking information (PDF).
From Philadelphia International Airport (PIA)
Driving: All major car rental companies are located at the airport.
Airport Train: The train leaves every half hour at 10 minutes and 40 minutes past the hour, and it arrives at University City Station on the HUP campus. The train costs approximately $5 and takes 20 minutes.
Taxi: A metered cab from the airport costs approximately $20 and the ride takes approximately 20 minutes.
Parking Garages
Parking garages are available at the Perelman Center for Advanced Medicine and the 3600 Civic Center Boulevard garage. Please note that the Penn Tower Garage has permanently closed.
A free shuttle service will be available to the Hospital of the University of Pennsylvania and the Perelman Center for Advanced Medicine on a continuous loop from the new 3600 Civic Center Boulevard garage Level 2 transportation center.
HUP Security also provides walking escorts to any employee, patient or visitor who requests an escort to parking garages, lots and streets surrounding the hospital perimeter. Escorts are always available — timing depends on security officer availability. Please call 215-662-2677 to request a walking escort.
Perelman Center for Advanced Medicine Parking Garage
3600 Civic Center Boulevard Parking Garage
- Hours: Opens Monday at 5 am and closes Friday at midnight; Closed on weekends
- Rates: $20 flat rate
- Directions from Spruce Street:
- From Spruce Street, turn onto 34th Street which becomes Civic Center Boulevard.
- Continue on Civic Center Boulevard and make a left onto West Service Drive. The entrance to the garage is on the right.
- Directions from University Avenue:
- From University Avenue, turn right onto Civic Center Boulevard and an immediate right onto Health Sciences Drive.
- Entrance to the garage will be on the left after the curve.
- See designated entrances to NEW 3600 Civic Center Boulevard parking garage on map.
Shuttle Service
A shuttle service will be available to the Hospital of the University of Pennsylvania and the Perelman Center for Advanced Medicine on a continuous loop from the new 3600 Civic Center Boulevard garage Level 2 transportation center.
Valet Parking
Long-Term Parking
For patients requiring an extended hospitalization, parking passes are available to family members at a discounted rate:
- 15 Day Pass: Allows unlimited in/out parking in the Perelman Center garage, or the 3600 Civic Center Boulevard garage for 15 consecutive days. (Cost: $80)
- 7 Day Pass: Allows unlimited in/out parking in the Perelman Center garage, or the 3600 Civic Center Boulevard garage for seven consecutive days. (Cost: $45)
- There is no reimbursement for days not used or lost/stolen cards.
- Long-term parking passes can be purchased at the Cashier's Booth located on the ground floor of the Perelman Center.