HTN and Obesity – Management of Hypertension in Obesity

  • Name of PI and Coordinator:
    Jordy Cohen, MD, Elkys Funez, Shira Blady
  • Contact:
    Elkys Funez – elkys.funez@uphs.upenn.edu
  • Purpose of Study/Patient Population: Antihypertensive class effects, blood pressure control, and renal and cardiac outcomes—The goal of this study is to evaluate the effect of obesity and body fat distribution on how blood pressure medication classes impact degree of blood pressure control.

Radiance-HTN TRIO

  • Name of PI, Sub I and Coordinator:
    Debbie Cohen, MD, Yonghong Huan, MD, Jordana Cohen, MD, Robin Neubauer, RN
  • Contact:
    Robin Neubauer – RN, robin.neubauer@uphs.upenn.edu, 215-615-0773
  • Purpose of Study/Patient Population: The purpose of the RADIANCE-HTN study is to demonstrate the ability of the Paradise System to effectively reduce systolic daytime ambulatory BP (ABP) in hypertensive subjects. In addition the study is designed to document the safety profile of the Paradise System in all treated subjects. All subjects will be required to also be taking either Exforge HCT or Tribenzor HCT, provided by the study sponsor starting at screening visit 1.

SPYRAL HTN-OFF MED

  • Name of PI, Sub I and Coordinator:
    Debbie Cohen, MD, Yonghong Huan, MD, Matt Denker, MD, Robin Neubauer, RN
  • Contact:
    Robin Neubauer, RN – robin.neubauer@uphs.upenn.edu, 215-615-0773
  • Purpose of Study/Patient Population:
    The purpose of this study is to provide additional information about a medical device intended to help treat high blood pressure in patients who are currently not taking medications for high blood pressure.

SPYRAL HTN-ON MED

  • Name of PI, Sub I and Coordinator:
    Debbie Cohen, MD, Yonghong Huan, MD, Matt Denker, MD; Robin Neubauer, RN
  • Contact:
    Robin Neubauer – robin.neubauer@uphs.upenn.edu, 215-615-0773
  • Purpose of Study/Patient Population:
    The purpose of this study is to provide additional information about a medical device intended to help treat high blood pressure in patients whose blood pressure is not controlled, despite treatment with three blood pressure medications.
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