Our approach to AERD treatment

Long-term relief from AERD symptoms is possible with our highly specialized treatment. Penn Medicine’s AERD Center gives you access to specialists with the expertise to provide a research-driven strategy that includes surgery and aspirin desensitization.

Male doctor examine a female patient

Redefining treatment for AERD

Many people who come to the Penn AERD Center have had multiple sinus surgeries, recurring nasal polyps, asthma, and other symptoms that haven’t improved with traditional treatments.

At Penn Medicine, we don’t just manage symptoms; we provide a definitive path forward. Our approach is built on a seamless partnership between allergy/immunology and rhinology specialists, ensuring that your diagnosis is thorough and your treatment plan is comprehensive from day one.

The pillars of our approach

We leverage decades of specialized experience and research-backed protocols to deliver results where traditional AERD treatments have failed. Our approach is built on three foundational pillars that ensure our patients achieve outcomes they couldn't find elsewhere.

  • Unmatched clinical expertise: Led by John V. Bosso, M.D., a pioneer in aspirin desensitization, our team specializes in the most complex AERD cases, successfully treating patients who have seen multiple doctors and had several surgeries without lasting relief.
  • One unified, multispecialty team: Providers with expertise in ear, nose, and throat (ENT) and rhinology work closely with our experts in allergy and immunology in a seamless partnership to evaluate, diagnose, and treat AERD.
  • The “Gold Standard” treatment protocol: Our proven "surgery-to-desensitization" pathway is designed to stop the cycle of polyp regrowth and restore your quality of life with long-term remission.

Your roadmap to long-term relief from AERD

Explore the core stages of AERD treatment

Our sinus surgeons perform hundreds of AERD surgeries a year, and our allergists have decades of experience providing aspirin desensitization. 

Our philosophy of care

Our medical director, Dr. John V. Bosso, and our specialized team have a long history of diagnosing and treating AERD. Dr. Bosso was one of the first specialists to be trained in aspirin desensitization and continues to research and study therapies that bring lasting results. Our AERD treatment approach can have a dramatic effect on your symptoms, helping you get back to enjoying the activities that matter to you.

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