Penn Medicine Provider
Medical Oncology
Ryan C. Massa, MD
5.0
(382)
Accepting new patients
Sees patients age 18 and up
Abramson Cancer Center Penn Presbyterian
View 1 additional location

About me

  • Associate Director for Network Development, Abramson Cancer Center
  • Assistant Professor of Clinical Medicine (Hematology-Oncology)

Education and training

  • Medical School: University of Maryland School of Medicine
  • Residency: University of Pittsburgh Medical Center
  • Fellowship: University of Pittsburgh Medical Center

What my patients think about me

Average Rating
5.0

382 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

April 2025
5.0
5.0
excellent dr
April 2025
5.0
5.0
very thorough
April 2025
5.0
5.0
very smart and to the point...answered every question l had
March 2025
5.0
5.0
dr. massa is probably the best doctor i have ever dealt with.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Massa is a Penn Medicine physician.

Qualifications and experience

My research

Cillo AR, Cardello C, Shan F, Karapetyan L, Kunning S, Sander C, Rush E, Karunamurthy A, Massa RC, Rohatgi A, Workman CJ, Kirkwood JM, Bruno TC, Vignali DAA. Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8(+) T cells to promote antitumor immunity , Cell, 187(16): 2024,4373-4388


Eads JR, Graham N, Gibson MK, Rajdev L, Chakravarthy AB, Khullar OV, Lin SH, Wistuba II, Agarwal R, Blazar M, Mehta DR, Al Baghdadi T, Jin N, Massa RC, Hamilton SR, Staley CA, Wong TZ, O'Dwyer PJ. A phase II/III study of peri-operative nivolumab (nivo) and ipilimumab (ipi) in patients (pts) with locoregional esophageal (E) and gastroesophageal junction (GEJ) adenocarcinoma: Results of the neoadjuvant pathologic complete response (pCR) rate (ECOG-ACRIN EA2174). , J Clin Oncol, American Society of Clinical Oncology Annual Meeting, Chicago, IL., 42: 2024,(suppl 16; abstr 4000)


Karapetya L, Karunamurthy A, Cillo A, Wang S, Massa RC, Rohatgi A, Deitrick C, Najjar YG, Davar D, Luke JJ, Sander C, Rose A, Rush E, Joy M, Kunning S, Bao R, Wang H, Bruno TC, Vignali DD, Kirkwood JM Randomized phase II evaluation of nivolumab (nivo), or relatlimab (rela), or combined nivo-rela lead-in followed by nivo-rela as first line therapy for patients (pts) with advanced melanoma (mel) , J Clin Oncol, American Society of Clinical Oncology Annual Meeting, Chicago, IL. , 42: 2024,(suppl 16; abstr 9525)


Tuteja S, Cayabyab MA, Hoffecker G, Varughese L, Wittner V, Ndayishmiye JDD, , Wang X, Harr M, Santani A, Hakonarson H, Massa RC, Damjanov N, Reddy NJ, Oyer RA, Teitelbaum UR Implementing DPYD/UGT1A1 testing to prevent treatment related adverse events (TRAE) in patients with gastrointestinal (GI) cancer: Results of a pragmatic implementation trial , J Clin Oncol, American Society of Clinical Oncology Annual Meeting, Chicago, IL. , 42: 2024,(suppl 16; abstr 10599)


Eads J, Chapin W, Massa R Defining the Role of Neoadjuvant Therapy for Gastroesophageal Cancers , Advances in Oncology, 4: 2024


Karasic TB, Brown TJ, Schneider C, Teitelbaum UR, Reiss KA, Mitchell TC, Massa RC, O'Hara MH, DiCicco L, Garcia-Marcano L, Amaravadi RK, O'Dwyer PJ. Phase I Trial of Regorafenib, Hydroxychloroquine, and Entinostat in Metastatic Colorectal Cancer , Oncologist, 27(9): 2022,716-e689


Reiss KA, Mick R, Teitelbaum U, O'Hara M, Schneider C, Massa R, Karasic T, Tondon R, Onyiah C, Gosselin MK, Donze A, Domchek SM, Vonderheide RH. Niraparib plus nivolumab or niraparib plus ipilimumab in patients with platinum-sensitive advanced pancreatic cancer: a randomised, phase 1b/2 trial , Lancet Oncol, 23(8): 2022,1009-1020.


Brown TJ, Massa RC. Challenges in the Management of Patients With HER2-Amplified Colorectal Cancer , JCO Oncol Pract, 18(8): 2022,555-556


Varughese LA, Bhupathiraju M, Hoffecker G, Terek S, Harr M, Hakonarson H, Cambareri C, Marini J, Landgraf J, Chen J, Kanter G, Lau-Min KS, Massa RC, Damjanov N, Reddy NJ, Oyer RA, Teitelbaum UR, Tuteja S. Implementing Pharmacogenetic Testing in Gastrointestinal Cancers (IMPACT-GI): Study Protocol for a Pragmatic Implementation Trial for Establishing DPYD and UGT1A1 Screening to Guide Chemotherapy Dosing , Front Oncol, 12: 2022,859846


Chapin WJ, Massa RC, Eads JR. Evolving standards of care for neoadjuvant and adjuvant therapy in esophageal, gastroesophageal junction, and gastric cancer , Clin Adv Hematol Oncol, 19(12): 2021,784-793