Giorgos C. Karakousis, MD

Endocrine and Oncologic Surgery

4.9 with 313 ratings

Sees patients age 18 and up

Speaks English and Greek

Giorgos C. Karakousis, MD

Endocrine and Oncologic Surgery

4.9 with 313 ratings

Sees patients age 18 and up

Speaks English and Greek

Chief, Division of Endocrine and Oncologic Surgery
Professor of Surgery at the Hospital of the University of Pennsylvania
Dr. Karakousis is a Penn Medicine physician.

Call 800-789-7366 Request Appointment

Meet Dr. Karakousis

Recognized by America's Top Doctors for 2017

Recognized in Philadelphia magazine's annual Top Docs issues, 2018 - 2021

Abdominal Cancer Surgery
Acral Lentiginous Melanoma
Adamantinoma
Alveolar Soft-Part Sarcoma
Angiosarcoma
Appendiceal Cancer (Appendix Cancer)
Appendiceal Cancer Surgery
Appendiceal Carcinoid
Atypical Lipomatous Tumor
Axillary Lymphadenopathy
Basosquamous Carcinoma
Benign Nerve Sheath Tumor
Benign Schwannoma
Bile Duct Cancer (Cholangiocarcinoma)
Cancer Risk Reduction Surgery
Cancer Surgery
Carcinoid of the Stomach
Carcinosarcoma
Chondrosarcoma
Clear Cell Sarcoma
Composite Hemangioendothelioma
Cytoreduction Surgery
Dedifferentiated Liposarcoma
Dermatofibrosarcoma Protuberans
Desmoid Tumor
Endovascular Papillary Angioendothelioma
Epithelioid Hemangioma
Epithelioid Rhabdomyosarcoma
Epithelioid Sarcoma
Ewings Sarcoma
Fibrosarcoma
Fibrosarcoma of Anterior Abdominal Wall
Gastrointestinal Cancer (GI Cancer)
Granular Cell Tumor
Groin Lymphadenopathy
Head and Neck Sarcoma
Hemangioendothelioma
Hemangiopericytoma
Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Laparotomy
Leiomyosarcoma
Limb Sparing Surgery
Liposarcoma
Liver Cancer
Liver Metastases
Lymph Node Dissection (Lymphadenectomy)
Malignant Fibrous Histiocytoma
Malignant Neoplasm of Soft Tissue
Malignant Peripheral Nerve Sheath Tumor
Malignant Schwannoma
Melanoma
Melanoma Surgery
Metastatic Colon Cancer
Metastatic Colorectal Cancer
Metastatic Melanoma
Minimally Invasive Lymph Node Dissection
Myxofibrosarcoma
Myxoid Liposarcoma
Neuroectodermal Tumor
Neuroendocrine Tumor
Neuroendocrine Tumor of the Appendix
Neuroendocrine Tumor of the Bowel
Neuroendocrine Tumor Surgery
Neurofibrosarcoma
Pancreas Removal Surgery (Pancreatectomy)
Pancreatic Cancer
Peritoneal Surface Malignancy
Pleomorphic Liposarcoma
Pleomorphic Sarcoma
Proximal Pancreatic Surgery (Pancreatectomy)
Radical Subtotal Pancreas Surgery
Rectal Cancer
Retiform Hemangioendothelioma
Retroperitoneal Liposarcoma
Retroperitoneal Sarcoma
Retroperitoneal Sarcoma Resection
Rhabdomyosarcoma
Sarcoma
Sarcoma Botryoides
Schwannoma
Sebaceous Carcinoma
Sentinel Lymph Node Biopsy
Sentinel Node Biopsy
Skin Cancer
Small Bowel Cancer
Soft Tissue Sarcoma Radical Tumor Resection
Soft Tissue Tumor (Connective Tissue Tumor)
Solitary Fibrous Tumor
Spitzoid Melanoma
Squamous Cell Carcinoma
Stomach Mass
Stomach Tumor Surgery
Stromal Tumor of the Intestine
Swollen Lymph Nodes
Synovial Sarcoma
Undifferentiated Pleomorphic Sarcoma
Undifferentiated Sarcoma
Well Differentiated Liposarcoma
Whipple Procedure
Wide Local Excision Surgery

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Programs and Centers

Penn Medicine's programs and centers combine doctors from many disciplines to coordinate care from start to finish. Dr. Karakousis is part of these programs:

Board Certification

Surgery, 2008

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania; Memorial Sloan-Kettering Cancer Center

Primary Location

Penn Endocrine and Oncologic Surgery Perelman 3rd Floor

Perelman Center for Advanced Medicine
Abramson Cancer Center, West Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104

Map Call 800-789-7366

View details

Penn Medicine Hospital Privileges

Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Overall Ratings

out of 5 ; Ratings;

The Patient Satisfaction Rating is an average of all responses to the care provider related question shown above from our internal platform, PMX Feedback. Responses are measured on a scale of 1 to 5 with 5 being the best score. Scores reflect either the most recent 12 months of surveys or the most recent 30 surveys overall. Data is updated monthly and comments remain on the profile for 12 months.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Patients that are treated in outpatient or hospital environments may receive different surveys.

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Aetna US Healthcare
Amerihealth Caritas
Amerihealth Caritas Medicare
Centivo Health Plan
Cigna
Cigna HealthSpring
Clover Health Plan
Devon Health Services (Americare)
Gateway Health Plan
Geisinger Health Plan
Geisinger Medicaid
Global Medical Management
HealthAmerica / HealthAssurance, a Coventry Plan
HealthPartners
HealthPartners Medicare
HealthSmart
Highmark Blue Shield
Homestead Smart Health Plans/Claim Watcher
Horizon Blue Cross Blue Shield of New Jersey
Humana / Choicecare

Humana / Medicare
Imagine Health 360
Independence Blue Cross (Keystone East)
Keystone First
Keystone First Medicare
Multiplan
NJ Medicaid
NJ Qualcare
Oscar Health Plan of PA
Oxford Health Plan
PA Health and Wellness (Centene) Medicare
PA Medicaid
PA Medicare
Provider Partners Health Plan
Rail Road Medicare / Palmetto GBA
Tricare
United Healthcare
UnitedHealthcare Community Plan
US Family Health Plan
Veterans Choice Program

Selected Publications

Vargas GM, Shafique N, Xu X, Karakousis G: Tumor-infiltrating lymphocytes as a prognostic and predictive factor for melanoma Expert Reviews of Molecular Diagnostics : 2024 (Epub).

Maker AV, Karakousis G: Educating cancer-associated fibroblasts (CAFs): Are they the student or the teacher? Annals of Surgical Oncology : 2024 (Epub).

Sharon CE, Karakousis GC: Neoadjuvant therapy for resectable melanoma Clinical & Experimental Metastasis : 2024 (Epub).

Miura J, Sabharwal S, Ghert M, Karakousis G, Roland CL: Great debate: Systematic re-resection after macroscopic complete unplanned excision of soft tissue sarcoma Annals of Surgical Oncology 31 (3): 2047-2050,2024.

Ma KL, Sharon CE, Tortorello GN, Keele L, Lukens JN, Karakousis GC, Miura JT: Delayed time to radiation and overall survival in Merkel cell carcinoma Journal of Surgical Oncology 128 (8): 1385-1393,2023.

Sharon CE, Karakousis GC: Educational Review: Neoadjuvant approaches to melanoma Annals of Surgical Oncology 29 (13): 8492-8500,2023.

Rose MA, Miura J, Sharon C, Ermer JP, Karakousis G, Wachtel H: Current patterns of treatment and outcomes in advanced melanoma at a single institution Journal of Surgical Oncology 291 : 25-33,2023.

Tortorello G, Sharon CE, Susman CG, Ma KL, Krouse RS, Lee MK, Miura JT, Karakousis GC: Disparities by race and ethnicity in surgical palliative care for pancreatic cancer Journal of the American College of Surgeons 237 (5 Suppl 1): S207,2023.

Wang K, Coutifaris P, Brocks D, Solis S, Han N, Manne S, Kiner E, Sachar C, George S, Yan P, Kiner MW, Laughlin AI, Kothari S, Giles JR, Mathew D, Ghinnagow R, Alanio C, Flowers A, Xu W, Tenney D, Xu X, Amaravadi RK, Karakousis GC, Schuchter LM, Buggert M, Wherry EJ, Minn A, Weber J, Mitchell T, Herati RS, Huang A: Reinvigoration of progenitor-exhausted CD8 T cells by anti-CTLA-4 contributes to the sustained activity of combination checkpoint blockade Journal for ImmunoTherapy of Cancer 11 (Suppl 2): A1759,2023.

Shannon AB, Karakousis GC: The impact of the COVID-19 pandemic on new diagnoses of melanoma: A response to additional multi-institution and international reports Journal of the American Academy of Dermatology 89 (5): e221-e222,2023.

Academic Contact Information

Division of Endocrine & Oncologic Surgery
Hospital of the University of Pennsylvania
3400 Spruce St., 4 Silverstein
Philadelphia, PA 19104
Phone: 215-662-2083
Patient appointments: 800-789-7366

American Board of Surgery Board Examiner, National
American College of Surgeons (ACS), National
American Society of Clinical Oncology (ASCO) Education Committee: Melanoma/Skin Cancers, National
Association for Academic Surgery, National
Complex General Surgical Oncology (CGSO) Board Examiner (through American Board of Surgery) for Certifying Exam, National
Consultant for the General Surgery Certifying Exam, Skin & Soft Tissue Committee, American Board of Surgery, National
Eastern Cooperative Oncology Group, National
Halsted Society, Audit Committee, National
Halsted Society, National
National Comprehensive Cancer Network Panel (Melanoma), National
Philadelphia Academy of Surgery, Local
Scientific Advisory Board, Melanoma International Foundation, National
Sentinel Lymph Node Working Group, National
Society of Nuclear Medicine & Molecular Imaging Appropriate Use Committee Expert Panel for Lymphoscintigraphy, National
Society of Surgical Oncology, National
Society of University Surgeons, National
Surgical Biology Club II, National