PHILADELPHIA — Mark L. Kahn, MD, professor of Medicine, Perelman School of Medicine at the University of Pennsylvania, received a five-year, $6 million grant from Paris-based Fondation Leducq to study lymphatic vascular defects and their contribution to common human cardiovascular diseases. Kahn and his lab team, including Zhiying Zou, Paul Hess, Zoltan Jakus, and Patty Mericko, lead the North American contingent of an international group that includes two other American and three European academic institutions.
The lymphatic vascular system comprises a large vascular network that regulates fluid balance, transports fats and coordinates immune responses in the body. The lymphatic system is poorly understood compared to the blood vascular system and its role in human vascular diseases is relatively unexplored. The project brings together the major labs investigating lymphatic vascular biology to understand the impact of lymphatic dysfunction on cardiovascular disease and to develop new therapies for lymphatic vascular diseases.
For more information please read the Fondation Leducq news release: http://fondationleducq.org/nivel2.aspx?idsec=1315
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