News Release

Philadelphia – New research from the University of Pennsylvania School of Medicine shows a substantial decrease in one type of revascularization procedure, coronary artery bypass graft (CABG) surgery, while rates of utilization of the other form, percutaneous coronary intervention (PCI), have remained unchanged. Coronary revascularization, the process of restoring the flow of oxygen and nutrients to the heart, is among the most common hospital-based major interventional procedures performed in the United States. Over the past decade, the field of coronary revascularization has been changed by a number of technological advances, including new devices and new surgical techniques for clearing blockages. The research is published in the May 4 edition of the Journal of the American Medical Association (JAMA).

“There has been a substantial decline in CABG surgery during the past decade without a commensurate decline in PCI, suggesting the likelihood that a coronary artery disease patient receives PCI versus CABG has markedly changed,” said Peter W. Groeneveld, MD, MS, the study’s corresponding author and assistant professor of Medicine at Penn.

The serial cross-sectional study used time trends of patients undergoing CABG surgery or a PCI procedure between 2001 and 2008 at U.S. hospitals in the Healthcare Cost and Utilization Project’s Nationwide Inpatient Sample (NIS), which reports inpatient coronary revascularizations, supplemented by Medicare data on outpatient revascularizations. The data come from a balanced sample of approximately 20 percent of U.S. hospitals, which are widely representative of nationwide cardiovascular care.

The data analysis revealed that there was a 15 percent decrease in the annual rate of coronary revascularizations overall between 2001 and 2008. The annual CABG surgery rate dropped by approximately 38 percent in that same time period, but PCI rates did not significantly change. The drop in CABG surgery rates was observed across sex, age, racial, and regional subgroups. The decrease in CABG surgeries occurred as a roughly linear trend throughout the sample time period, suggesting that the decrease was not triggered by any single event, such as the introduction of a particular new technology or a clinical guideline.

Interestingly, the researchers also found that despite the decline in CABG surgery rates between 2001 and 2008, the number of hospitals in the sample providing CABG surgery actually increased by 12 percent, while the number of PCI hospitals increased by 26 percent.

“Our data imply a sizeable shift in cardiovascular clinical practice patterns away from surgical treatment toward percutaneous, catheter-based interventions,” said Dr. Groeneveld. “This is concerning given that recent data from a national trial indicated CABG surgery remains the better choice for patients with previously untreated three-vessel or left main coronary artery disease.”

The authors note that the NIS does not include detailed information about patient clinical characteristics, such as coronary anatomy, angina class, ejection fraction, medications, surgical risk, or smoking status, which could explain some of the changes over time in utilization of CABG surgery or PCI.

For more information, please see the JAMA press release and the research paper online.


Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $5.3 billion enterprise.

The Perelman School of Medicine has been ranked among the top five medical schools in the United States for the past 18 years, according to U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $373 million awarded in the 2015 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center -- which are recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report -- Chester County Hospital; Lancaster General Health; Penn Wissahickon Hospice; and Pennsylvania Hospital -- the nation's first hospital, founded in 1751. Additional affiliated inpatient care facilities and services throughout the Philadelphia region include Chestnut Hill Hospital and Good Shepherd Penn Partners, a partnership between Good Shepherd Rehabilitation Network and Penn Medicine.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2015, Penn Medicine provided $253.3 million to benefit our community.

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