News Release

PHILADELPHIA — More than 200,000 people are treated for cardiac arrest in United States hospitals each year, a rate that may be on the rise. The findings are reported online this week in Critical Care Medicine in a University of Pennsylvania Perelman School of Medicine-led study.

Though cardiac arrest is known to be a chief contributor to in-hospital deaths, no uniform reporting requirements exist across the nation, leaving experts previously unable to calculate its true incidence and study trends in cardiac arrest mortality and best practices in resuscitation care.

The authors, led by Raina M. Merchant, MD, MS, an assistant professor of Emergency Medicine, used three different approaches — involving the American Heart Association's Get With the Guidelines data, a voluntary registry of hospital resuscitation events - to estimate the total number of treated cardiac arrests that take place in United States hospitals each year.

While some of these events occur among terminally ill patients, the authors suggest that many of the cardiac arrests they catalogued may be preventable through better monitoring of patients, quicker response time to administer CPR and defibrillation, and improved adherence to best practices in resuscitation guidelines. Patients who suffer in-hospital cardiac arrests are more than twice as likely to survive than those who arrest in public settings -- 21 percent survive to go home, compared to less than 10 percent of out-of-hospital cardiac arrest patients — but both areas suggest opportunities to improve and standardize care.

"Our study proves that cardiac arrest represents a tremendous problem for hospitals in the United States," Merchant says. "Until now, we could only guess about how many patients were suffering these events. It's impossible to make improvements in something we can't measure. These numbers finally provide us with a roadmap for improving allocation of resources to care for these critically ill patients and further our study of ways to identify patients who are at risk of cardiac arrest in the hospital and improve survival."

 

Penn Medicine is one of the world’s leading academic medical centers, dedicated to the related missions of medical education, biomedical research, excellence in patient care, and community service. The organization consists of the University of Pennsylvania Health System and Penn’s Raymond and Ruth Perelman School of Medicine, founded in 1765 as the nation’s first medical school.

The Perelman School of Medicine is consistently among the nation's top recipients of funding from the National Institutes of Health, with $550 million awarded in the 2022 fiscal year. Home to a proud history of “firsts” in medicine, Penn Medicine teams have pioneered discoveries and innovations that have shaped modern medicine, including recent breakthroughs such as CAR T cell therapy for cancer and the mRNA technology used in COVID-19 vaccines.

The University of Pennsylvania Health System’s patient care facilities stretch from the Susquehanna River in Pennsylvania to the New Jersey shore. These include the Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, Chester County Hospital, Lancaster General Health, Penn Medicine Princeton Health, and Pennsylvania Hospital—the nation’s first hospital, founded in 1751. Additional facilities and enterprises include Good Shepherd Penn Partners, Penn Medicine at Home, Lancaster Behavioral Health Hospital, and Princeton House Behavioral Health, among others.

Penn Medicine is an $11.1 billion enterprise powered by more than 49,000 talented faculty and staff.

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