Address: 800 Spruce Street, Philadelphia, PA 19107

• From Northeastern Areas
  From I-95 South, follow Exit 22 for I-676/US-30/Callowhill Street exit towards Central Philadelphia/Independence Hall. Turn right onto Callowhill Street, then after about a half-mile turn left onto North 6th Street. Make a right onto Spruce Street and follow for 2 blocks. Hospital is located at 8th and Spruce Streets.

• From the West
  Take the Pennsylvania Turnpike to Exit 326 (old exit 24), Valley Forge. Take I-76 East approximately 17 miles to Exit 344 on the left towards Central Philadelphia. Merge onto the Vine Street Expressway for about 1.5 miles, then take the exit towards I-676 E/US-30 E/Ben Franklin Bridge. Make a right onto North 6th Street and follow for 0.8 miles. Turn right onto Spruce Street and follow for two blocks. Hospital is located at 8th and Spruce Streets.

• From the North
  Take I-476 South to Exit 16, towards Philadelphia/Valley Forge. Merge onto I-76 E for about 12.6 miles, then take I-676E exit 344 on the left towards Central Philadelphia. Merge onto the Vine Street Expressway for about 1.5 miles, then take the exit towards I-676 E/US-30 E/Ben Franklin Bridge. Make a right onto North 6th Street and follow for 0.8 miles. Take a right onto Spruce Street and follow for 2 blocks. Hospital is located at 8th and Spruce Streets.

• From the South
  Take I-95 North to the Columbus Blvd. (Exit 20) towards Washington Ave. Keep left at the fork in the ramp, and turn left onto South Columbus Blvd. Follow Columbus Boulevard to the next traffic light and turn left on Washington Avenue. Stay on Washington Avenue to 7th Street and turn right. Take 7th Street to Spruce Street and turn left. Follow Spruce Street one block to the hospital, at 8th and Spruce Streets.

• From New Jersey
  Take the New Jersey Turnpike to Exit 3, then the Black Horse Pike (Rte. 168 North) for one mile to I-295 South. Take the Rt. 70 W exit, number 34B, towards Cherry Hill/Camden. Merge onto NJ-70 W and continue for approximately 5 miles, then take the Rt-38 W ramp that merges onto Kaighn Ave. Stay straight to go onto US-30 W, and take the I-676 W/US-30 W ramp. Cross the Ben Franklin Bridge, and at the bottom of the exit ramp on Vine Street, bear left to follow the signs to "8th Street South." Follow 8th Street to Spruce Street.

• Alternate Route from New Jersey and points East
  Take Route 70 West to the Rt-38 W ramp that merges onto Kaighn Ave. Stay straight to go onto US-30 W, and take the I-676 W/US-30 W ramp. Cross the Benjamin Franklin Bridge, and follow to the bottom of the exit ramp on Vine Street. Bear left to follow the signs to "8th Street South." Follow S. 8th Street to Spruce Street.

• From Montgomery County
  Take I-76 East to the I-676E exit, number 344, on the left towards Central Philadelphia. Merge onto the Vine Street Expressway, and continue towards the 8th Street exit. Follow 8th Street to Spruce Street.

• From West of Philadelphia
  Travel east on Market Street. Make a right onto S.15th Street, and then a left onto S. Penn Square. Turn left onto S. Juniper Street and then another right onto Market Street. Follow Market Street until making a right onto S. 8th Street. Continue on 8th Street about a half-mile until you reach Spruce Street. Hospital is located at 8th and Spruce.

• From Northeast Philadelphia
  Take Roosevelt Blvd. to I-76 East. Take I-76 East to Exit 344 for I-676 E. Take I-676 E (Vine Street Expressway) to the 8th Street Exit. Follow 8th Street to Spruce Street.

Visitors may park in the hospital's parking decks for a fee.

Parking Garages

• Deck 1
  
  • Location: 8th & Delancey Streets
    (Entrance on Delancey Street)
  • Hours: Open 24 hours a day
• Deck 2
  
  • Location: 7th & Delancey Streets
    (Entrance on Delancey Street)
  • Hours: Monday to Friday: 6 am to 11 pm (closed on weekends)

Valet Parking

Valet service is temporarily suspended at all Penn Medicine locations to limit COVID-19 exposure.

• AMTRAK
  Northeast corridor AMTRAK trains stop at 30th Street Station. See SEPTA Regional Rail Lines or SEPTA City Transit for information on traveling to Pennsylvania Hospital from 30th Street Station. Taxi service also is available at 30th Street Station.

  AMTRAK Information: 215-824-1600 or 800-USA-RAIL

• SEPTA Regional Rail Lines
  All SEPTA Regional Rail Lines stop at Jefferson Station (11th and Market streets, formerly Market East station). From there, walk three blocks east on Market Street to 8th Street. Turn right on 8th Street and then walk five blocks south to Spruce Street.

• SEPTA City Transit
  SEPTA Information: 215-580-7800, septa.org

  • From West or Northeast Philadelphia:
    Take the Market-Frankford (Blue Line) elevated train/subway to the 8th Street station. Walk five blocks south, or take the #47 bus south, on 8th Street to Spruce Street.

  • From North or South Philadelphia:
    Take the Broad Street (Orange Line) subway to the Lombard/South station. From Broad and Lombard, walk east six blocks on Lombard Street, turn left at 8th Street, and walk two blocks on 8th Street to Spruce Street. Or take the #40 bus east to 8th and South Streets, then walk three blocks north to Spruce Street.

  • From the Airport:
    Leaves every half hour at 10 minutes and 40 minutes past the hour, arrives at Jefferson Station (11th and Market, formerly Market East station). The train costs about $5 and takes about 30 minutes. From there, take the Market-Frankford (Blue Line) elevated train/subway to the 8th Street station. Walk five blocks south, or take the #47 bus south, on 8th Street to Spruce Street.

• New Jersey PATCO Trains
  Take the PATCO line to 8th and Market streets. From there, walk five blocks south, or take the #47 bus south, on 8th Street to Spruce Street.

  PATCO Information: 215-922-4600, 609-772-6900

• Greyhound Bus Lines
  From the Greyhound Bus Station at 10th and Filbert streets, walk one block south to 10th and Market streets. From there, turn left and walk two blocks to 8th and Market streets. At 8th and Market, turn right and walk five blocks south to 8th and Spruce streets. Or, from the Greyhound Bus Station, take the Market-Frankford (Blue Line) elevated train/subway to the 8th Street station. From there, walk five blocks south, or take the #47 bus south, on 8th Street to Spruce Street.

  A taxi ride from the Greyhound Bus station costs about $6.

  Greyhound Bus Information: 800-231-2222