Uterine fibroids (leiomyomas)

What are uterine fibroids?

Uterine fibroids are non-cancerous tumors that form from muscular tissue on the uterine wall. You can develop one or several fibroids. These tumors can range in size from as small as a seed to as large as a grapefruit, distorting and enlarging the uterus. These growths are almost always benign. The chance of uterine fibroids developing into cancer is very rare – only one in 1,000 will turn out to be cancerous. If you have uterine fibroids, it doesn’t mean you have an increased chance of developing a cancerous fibroid or another form of cancer in the uterus.

Fibroids are most common in women in their 40s and early 50s. While they are very common, many women don’t know they have fibroids since they are too small to produce any symptoms. If the fibroids are large enough to cause issues, they can cause extreme discomfort, abdominal distension, pain, heavy menstrual bleeding, and frequent urination.

What are the symptoms of uterine fibroids?

In women who have symptoms, they usually experience the following:

  • Heavy bleeding during your menstrual cycle
  • Prolonged bleeding during your menstrual cycle lasting seven days or more
  • Frequent urination
  • Pelvic pressure or pain
  • Constipation
  • Difficulty emptying your bladder
  • Pain during sex
  • Lower back pain
  • Complications during pregnancy and labor

What causes uterine fibroids?

The exact cause of uterine fibroids isn’t clear. However, several factors contribute to their development, including:

  • Hormones: estrogen and progesterone are the two hormones that stimulate the development of the uterine lining each month as the body prepares for pregnancy. These hormones also affect the growth of the fibroids, which shrink after menopause and when anti-hormone medications are used.
  • Genetic: there is some evidence that uterine fibroids run in families. If your mother or grandmother developed fibroids, you may be more likely to develop them as well.

Diagnosis of uterine fibroids

Your physician can discover fibroids during a routine pelvic exam while checking the uterus, ovaries, and vagina. The following imaging tests will further confirm the existence of fibroids:

  • Ultrasound
  • MRI
  • X-Ray
  • CT Scan

Once a detailed diagnosis is reached, your physician will determine the best treatment options for you.

Treatment at Penn Medicine

The type of treatment you receive depends on your age, the severity of your condition, the type of fibroids you have, and whether you’re pregnant or wish to have children in the future.

Treatment that helps control fibroid symptoms include:

  • Birth control pills
  • Intrauterine devices (IUDs) that release hormones
  • Iron supplements to prevent or treat anemia caused by heavy periods
  • Pain relievers
  • Hormone therapy shots
  • Monitoring through regular pelvic exams

If your condition can’t be controlled by medications or hormones, you may require surgery. The specialists at Penn Medicine’s Department for Advanced Gynecologic Surgery have years of experience caring for women with some of the most complex gynecological conditions.

Penn Medicine surgeons and physicians offer new techniques in minimally invasive and robotic-assisted surgery for conditions like uterine fibroids. These methods lead to shortened recovery times, reduced pain, and blood loss; letting you get back to your life in record time.

When you choose Penn Medicine, you choose to work with a dedicated team that continues to lead the field; advancing the science of gynecologic medicine.

Related specialties

Patient stories

A grateful patient pays it forward to treat uterine cancers

Dalia Jakas credits her doctor with curing her uterine cancer without harming her quality of life. Now, she’s paying it forward for future patients.

Welcoming the first babies from Penn Fertility in Lancaster

Penn Fertility in Lancaster celebrated its first patients to have babies through the new practice.

Faith, fate, and families

At the Basser Center for BRCA at Penn, a unique philanthropic investment is making rapid progress toward preventing and treating heritable cancer.

Finding triple-negative breast cancer at 33, she chose ‘Team Penn’

Shocked to learn she had stage III breast cancer, Kate Korson knew just where to go. She flew home to Penn Medicine, where a clinical trial saved her life.

Home-assisted ventilation for autoimmune disease: Kim’s story

A rare autoimmune disease kept Kim Day from his favorite outdoor hobbies, until he met doctors in the Fishman Program for Home Assisted Ventilation.

CNN anchor Kasie Hunt had brain surgery at Penn

Before starting her own daily news show, journalist Kasie Hunt came to Penn Medicine for a growing brain tumor that was causing painful headaches.

A journey from battlefield to beating cancer

Andrew Camponelli was a young Army helicopter pilot in Kuwait when he was diagnosed with stage 3 melanoma.

Preschool teacher's journey to pain-free living

A preschool teacher in her forties is back to moving pain-free with knee and hip replacements.

Patient puts national spotlight on cancer clinical trials

As Kate Korson recently shared on Good Morning America, both she and her mother participated in clinical trials at Abramson Cancer Center.

A personal perspective on gender-affirming care

A lifelong performer shares how she began enjoying life even more after facial feminization surgery, as part of her gender-affirming care.

Schedule an appointment

We can help you schedule an appointment or you can search our directory of specialists.