Along with providing quality care to our patients, the expert team at the Penn Transplant Institute conducts clinical trials and research to develop new treatments and improve the lives of our patients before, during and after liver transplantation.

Penn Medicine frequently adds and updates clinical trials. Patients may search for ongoing trials and volunteer to participate in studies to develop new diagnostic and clinical treatments and improve current standards of care.

Liver Transplant Clinical Trials and Research at Penn 

Penn Transplant Biobank and Registry (BioTip)

Investigator: Kim Olthoff, MD

The purpose of the study is to see if substances in the donor organ can predict how well the organ will function after transplant. Tests on blood, urine and biopsy tissue samples will be used in this study to see if such a link exists. Patients who are expected to receive other organs (kidney, lung and heart) will also be part of this study. The research team will be looking at any injuries in the transplanted organs to see if there are similarities among the different organ groups. In this way, they hope to develop a better understanding of organ injury after transplant. Study participation lasts for the lifetime of the participant.

Research Coordinator: Mary Shaw, RN, BBA
Phone: 215-614-0528
Email: Mary.Shaw@pennmedicine.upenn.edu

Safety and Immunogenicity of SARS-COVID-19 Vaccine in Solid Organ Transplant Recipients and Candidates

CO PIs: Emily Blumberg, MD and Nina Luning Prak, MD, PhD

The purpose of this study is to evaluate the effectiveness of the COVID vaccine on patients awaiting an organ transplant and those who have received a transplant. Clinical trials conducted before distribution of the vaccines did not include the organ transplant population or those individuals awaiting transplant. As such, no data is available regarding the effectiveness or safety of the vaccine in these patients. This study includes all patients who are listed for or who have received an organ transplant from the following groups: heart, lung, liver, kidney, as well as combined organ transplants.

We will be collecting blood samples and health data. Participation begins immediately prior to the first dose of the COVID vaccine and lasts for one year. 

Research Coordinator: Mary Shaw, RN, BBA
Phone: 215-614-0528
Email: Mary.Shaw@pennmedicine.upenn.edu

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