Penn Medicine offers information about current research and clinical trials that enhance our heart transplant program.

Patients at Penn have access to clinical research and clinical trials investigating new treatments for congestive heart failure and cardiomyopathy.

Individuals with advanced heart failure may be considered for investigational mechanical heart pumps or new techniques in heart transplantation.

See below for heart transplant clinical trials conducted at Penn.

Human heart tissue protocol

Investigator: Kenneth Margulies, MD

Sponsored by: National Institutes of Health (NIH)

Clinical Trials in Organ Transplantation (CTOT) Studies 

Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation 

Investigator: Lee Goldberg, MD Sponsored by: National Institutes of Health (NIH) 

A Prospective, Randomized, Multicenter, Two-Parallel Arm Study Evaluating the Overall Efficacy and Safety of Desensitization Therapy on Selected Patients Awaiting Heart Transplantation 

Investigator: Lee Goldberg, MD Sponsored by: National Institutes of Health (NIH)

For more information about clinical trials at the Penn Transplant Institute, see Research & Clinical Trials.

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