Uterus transplant
We’re expanding what’s possible with infertility treatment through uterus transplantation. This groundbreaking option allows women with uterine factor infertility (UFI) to achieve their dreams of carrying and delivering a baby.
A groundbreaking new pathway to parenthood with uterus transplantation
A diagnosis of uterine factor infertility (UFI) can be heartbreaking for those who want children. In the past, people with UFI were told it wasn’t possible to carry and deliver a child. But uterus transplantation research is changing this. At the Penn Transplant Institute, our patients with UFI have the opportunity to carry and deliver a baby.
Our pioneering uterus transplant team consists of dozens of experts across several departments. We’re one of the only centers in the world to successfully perform uterus transplants from both living organ donors and deceased donors to recipients who went on to have healthy babies. We’re proud that our research is advancing fertility medicine and expanding the possibilities for hopeful parents-to-be.
The uterus transplant trial at Penn Medicine has completed its research phase. We are now excited to offer uterus transplantation as a standard medical service to those that qualify.
Donate or receive a uterus at Penn Medicine
At Penn Medicine, we understand the profound dream of parenthood. For those hoping to carry a child, or for those considering an extraordinary act of kindness, the gift of uterus donation is a remarkable journey. Discover how you can take part, either by receiving this gift or by giving it.
If you are interested in uterus donation, please fill out our uterus donor intake form.
If you're interested in receiving a uterus transplant from a donor, please fill out our uterus recipient intake form.
Understanding the uterine transplant procedure
This innovative surgery allows those without a uterus to experience pregnancy and childbirth by placing a healthy uterus from a donor into a recipient. The Penn Transplant Institute is recognized among the most skilled worldwide in performing this complex procedure, and is there for both donors and recipients throughout the entire surgical journey, from preparation to recovery.
Clinical trials
Clinical trials offer patients the opportunity to try new and effective treatments and take part in future research.
Second opinions
If you've received a diagnosis, our team of experts offers second opinions to grant you peace of mind.
Giving to the Transplant Institute
Your gift enables our researchers and clinicians to continue life-saving transplant programs.
Global leaders in uterus transplantation
Uterus transplant surgery is an emerging option in fertility treatment. Only a handful of centers around the world have the expertise to do this life-changing surgery. Penn Medicine’s UNTIL (Uterus Transplantation for Uterine Factor Infertility) trial welcomed its first baby in 2019—only the second baby in the United States born from a uterus from a deceased donor. Of our six uterus transplants, 4 have been from living donors, and we have delivered 7 babies so far, highlighting the continued success of our groundbreaking program.
Our program is one of few to explore donation from both living and deceased donors. This approach has the potential to expand the pool of available organs and make uterus transplant available to more women.
Our mission is to help everyone experiencing infertility achieve their dream of having children. We understand the emotional challenges of infertility and are here with compassionate care while you decide if uterine transplant is right for you.
Uterus donation requirements
If you have completed your childbearing and wish to give this gift to a woman diagnosed with UFI, you can donate your uterus for transplantation. Uterus donors must be between 30 and 50 years old and in good health. Additional requirements include:
- Body mass index (BMI) less than 30
- Cancer-free for at least five years
- No history of diabetes