PMOS care

Polyendocrine metabolic ovarian syndrome (PMOS) is a lifelong condition affecting menstrual cycles, fertility, cardiometabolic health, and mental health. Penn Medicine’s specialists provide comprehensive care and the latest, most effective treatments.
Female doctor holds a digital tablet while listening attentively to the unrecognizable female patient

Personalized treatment by compassionate PMOS specialists

Polyendocrine metabolic ovarian syndrome (PMOS), formerly referred to as polycystic ovary syndrome (PCOS), is a common condition experienced by 10 percent of females, beginning in adolescence. It is a genetic condition that may result in an imbalance of ovarian hormones and insulin resistance.

Our PMOS care team has expertise in treating all symptoms and related conditions using the latest therapies. We offer comprehensive care with a personalized treatment plan that addresses your unique symptoms and needs.

We know PMOS can be challenging for people experiencing it, especially if you’re trying to get pregnant. Our team offers compassionate fertility and reproductive support and education as we guide you through your journey.

Comprehensive specialist care and clinical research for PMOS

For complex cases, we offer care across a spectrum of disciplines at the Penn Medicine specialized center in downtown Philadelphia.

At the center, you receive an accurate diagnosis, effective treatments, and support. We also offer access to opportunities to participate in clinical research studies that advance the field of PMOS care.

Our PMOS management

PMOS affects each person differently. The specialists at Penn Medicine understand the complexity of PMOS and the care required to manage it. Our team includes experts from a variety of fields, including:

PMOS treatment options

PMOS is a complex condition with a wide range of symptoms and related health issues. Because the experience of PMOS differs from one person to another, treatments will vary as well.

Depending on your symptoms and related conditions, we may recommend lifestyle modifications, such as diet and exercise. We may also prescribe medications to manage diabetes or regulate your hormones. For fertility issues caused by PMOS, we may recommend one or more of the following treatments:

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Our doctors

Our providers work with you to plan and deliver exceptional treatment and personalized care.

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Locations

Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.

Related articles

Women with PCOS on birth control do not raise certain risks

Birth control, taken alone or paired with metformin, did not raise metabolic syndrome risk, a precursor of heart disease and diabetes, in women with PCOS.

  • December 22, 2025

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