The neurosurgeons at Penn Medicine's Center for Functional and Restorative Neurosurgery are world leaders in breakthrough surgical treatments for patients with movement disorders including Parkinson's disease, tremor from multiple sclerosis or other causes, dystonia, and medically intractable epilepsy.

Penn neurosurgeons are pioneers in the use of deep brain stimulation (DBS). This life-changing procedure can greatly reduce motor symptoms that accompany Parkinson's disease or other conditions and improve patients' abilities to perform daily activities. More than 900 patients have received DBS treatment at Penn, making it one of the largest treatment centers in the United States.

The Center for Functional and Restorative Neurosurgery also serves as the surgery center for the restoration of function affected by neurological disease and is an international training center for surgeons in the field. In addition to DBS, neurosurgeons at the center perform vagal nerve stimulation and targeted cranial resection for treatment of medically refractory epilepsy.


The Penn Center for Functional and Restorative Neurosurgery sponsors a host of clinical trials. Current trials include:

Penn neurosurgeons are investigating innovative technology to make surgery safer and more effective, and expanding their research focus to include neuro-psychiatric conditions such as depression under careful clinical trial protocols.

In This Section

Patient Stories

Hear the stories of patients who Penn Medicine has helped to break through their darkness and find new hope.

Treatments and Procedures

We offer leading-edge surgical techniques that focus on the restoration of motor function affected by neurological disease.

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