What causes lung nodules and lesions?
These abnormal lung tissues may develop due to infections, inflammation, tumors, or other conditions.
Benign pulmonary nodules and lesions are noncancerous growths that may result from:
- Infections: Bacterial and fungal infections can cause inflammation, leading to granulomas—small clumps of inflamed tissue.
- Inflammatory conditions: Diseases like rheumatoid arthritis or pulmonary sarcoidosis can trigger noninfectious lung inflammation, forming nodules.
- Noncancerous tumors: Hamartomas, the most common type, contain normal lung tissue like fat and cartilage. Less common benign tumors include chondromas, fibromas, and lipomas.
- Scar tissue: Previous lung infections or injuries can leave scar tissue that forms lesions.
- Lung cysts and abscesses: These conditions may also cause benign nodules to form.
Malignant pulmonary nodules and lesions are cancerous growths that can develop from:
- Primary lung cancer: Malignant lung nodules can develop as an early sign of lung cancer. Smoking is the leading cause, but other risk factors include exposure to secondhand smoke and certain airborne or occupational chemicals. Genetic factors may also play a role.
- Metastatic cancer: Cancers from other parts of the body can spread to the lungs and form malignant nodules.