Platelet-rich plasma (PRP) injections

People eligible for platelet-rich plasma injections are typically those seeking treatment for various conditions that may benefit from enhanced healing and tissue regeneration. PRP injections are often recommended for:

• Athletes or active individuals with soft tissue injuries
• Patients with arthritis looking to reduce pain and improve joint function
• People with chronic pain in areas like the shoulder, hip, knee, or lower back
• Those with hair loss conditions to stimulate hair growth
• Individuals recovering from surgery who want to accelerate the healing process in tissues like tendons or muscles

PRP injections are generally considered for people who have not responded well to treatments like physical therapy, rest, or medications. However, PRP may not be for everyone. Talk with your care team to determine if PRP therapy is right for you.

Platelet-rich plasma is created by removing a small amount of your blood, processing it to isolate the platelets, and then injecting the concentrated platelets into the area that needs treatment.

During the procedure, you can expect:

• A small amount of blood is drawn from your arm, like during a routine blood test.
• The collected blood is placed in a machine called a centrifuge, which spins it at high speeds. This process separates the blood into different components: red blood cells, plasma, and platelets. The platelet-rich plasma is then removed for use.
• Depending on the area being treated, local anesthesia may be applied to reduce discomfort during the injection.
• The concentrated PRP is injected directly into the targeted area, such as joints, tendons, muscles, skin, or scalp.
• The entire process typically takes about 30 to 60 minutes.

In some cases, you may need multiple PRP sessions for the best results. Your provider will talk to you about the best treatment plan for your specific situation.

Recovering from PRP injections is usually a straightforward process, though it varies depending on the area treated and the condition being addressed.

• Mild soreness, swelling, or stiffness at the injection site is common for the first few days.
• Avoid anti-inflammatory medications, as they can interfere with the healing process PRP is meant to support.
• It’s best to avoid strenuous activities for a day or two following the injection. Light movements or stretching may be recommended to help recovery depending on the area treated.

PRP stimulates healing, but improvements may take a few weeks to become noticeable, with full benefits often appearing over several months. Your health-care provider may schedule a follow-up visit to monitor progress.

PRP injections carry minimal risk of infection, and serious side effects or complications are extremely rare. While minor pain at the injection site is common in the short term, it can typically be managed with over-the-counter pain relievers.

Choosing Penn Medicine for PRP injections means you’ll receive care from experts at the forefront of advanced regenerative medicine. When you partner with us, you can expect:

• Experienced specialists: Our team includes experts in sports medicine, physical medicine and rehabilitation, orthopaedics, and dermatology, as well as other specialists with extensive experience in administering PRP therapy for various conditions, ensuring you receive expert care tailored to your needs.
• Individualized treatment plans: Our multidisciplinary approach allows us to develop customized treatment plans based on your condition, medical history, and recovery goals.
• State-of-the-art facilities: Our centers across the greater Philadelphia, Lancaster, and Princeton regions are equipped with advanced medical technology, providing high-quality care in a comfortable, modern setting.
• Complete care: You’ll benefit from access to a full range of supportive services, including physical therapy and rehabilitation, to ensure a smooth recovery and the best possible outcome.