Biliary and pancreatic disease care

When your digestive system stops working the way it should, it can take highly specialized care to get you back on track. Penn Medicine uses the latest technology to diagnose and treat all disorders of the pancreas, gallbladder, and bile ducts.

Digital composite of highlighted red pancreas of woman

High-quality, patient-focused pancreatic care

Nearly 25 million Americans are affected by biliary and pancreatic disorders, from gallstones and bile duct issues to pancreatic cysts and cancer. At Penn Medicine, our specialists focus on these conditions every day, using advanced imaging, minimally invasive procedures, and complex surgeries like the Whipple procedure and total pancreatectomy with auto islet cell transplantation (TPIAT) to achieve the best outcomes.

As a Pancreatic Disease Center of Excellence and a high-volume surgical center, we handle some of the most challenging cases in the country. You can expect collaborative care from experts across multiple disciplines, with guidance every step of the way.

Conditions we treat

Pancreatic Disease Center of Excellence

Penn Medicine is recognized as a Center of Academic and Clinical Excellence for Pancreatitis by the National Pancreas Foundation (NPF). This designation is given to programs that meet strict standards for patient care and research. Our team of specialists includes gastroenterologists, pancreatic surgeons, and interventional radiologists, along with experts in pain management, nutrition, psychosocial support, and more. Together, we treat acute and chronic pancreatitis, including rare forms like hereditary and autoimmune pancreatitis.

Pancreatic Disease Center of Excellence

Pioneering techniques for accurate diagnosis and care

We offer advanced testing and treatment for all biliary and pancreatic diseases, from benign conditions to complex cancers involving the pancreas, bile ducts, gallbladder, and duodenum.

3D Illustration of Human Body Organs Anatomy (Pancreas)

Unmatched experience in hepatobiliary and pancreas surgery

Penn Medicine is dedicated to ensuring the innovative treatments we develop reach the patients who need them most. We recognize that high costs and health disparities often hinder access to new treatments. To bridge these gaps, Penn Medicine is working on cost-effective, off-the-shelf CAR T therapies to reduce treatment costs. We also are enhancing access to clinical trials for underrepresented communities through community outreach and transportation support. Globally, Penn collaborates with regions like Costa Rica and Thailand to develop local manufacturing capabilities for CAR T therapies and mRNA vaccines, aiming for broader and more equitable health care access worldwide. 

Pancreatic Cyst Program

Penn Medicine’s Pancreatic Cyst Program is one of the few in the country dedicated to evaluating, treating, and monitoring pancreatic cysts. Each year, we care for more than 1,000 people, helping determine when a cyst can be safely watched and when treatment may be needed. Whether you’re newly diagnosed, unsure about the cause of a cyst, or seeking a second opinion, our program provides clear guidance. Our team also participates in ongoing research, so you’ll have access to the most promising advances in care.

Diverse team of doctors having a discussion

Our doctors

Our providers work with you to plan and deliver exceptional treatment and personalized care.

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Locations

Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.

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