Anuja Dokras, MD, PhD, Anastassia Amaro, MD, and Kelly Costello Allison, PhD

Talk recorded by CureTalks on December 19, 2018 at 10 am ET

Polycystic ovary syndrome (PCOS) is a health condition that affects 1 in 10 women of childbearing age. Women with PCOS have a hormonal imbalance and metabolism problems that may lead to obesity, cardiovascular disease, type 2 diabetes, infertility, endometrial cancer and more. In the absence of a complete cure, efficient management of the condition gains importance and information is the key. 

Penn Medicine's Anuja Dokras, MD, PhD, Director the PCOS Center, is the leader of the PCOS-COMET study being conducted to compare the effects of medications on metabolic risk factors such as weight, blood pressure, glucose, and cholesterol levels in overweight/obese women. In the following interview, Dr. Dokras, Anastassia Amaro, MD, and Kelly Costello Allison, PhD, from the Center for Weight and Eating Disorders of University of Pennsylvania, take a deep dive into the nuances of weight, nutrition, psychology and related effects on PCOS and its management.

David Goldberg, MD, and Peter Reese, MD

Talk recorded by CureTalks on November 13, 2018 at 2 pm ET

Of the nearly 100,000 people waiting for a kidney transplant in the US, many will never get one. Meanwhile, hundreds of Hepatitis C infected organs are discarded because of the infection.

Penn Medicine's David Goldberg, MD, and Peter Reese, MD, led a study that successfully showed that it is possible to transplant Hepatitis C infected kidneys into a patient and treat the disease in the recipient -- thereby, saving his or her life. In the following interview, Drs. Goldberg and Reese discuss how the treatment works and how they are expanding the process to transplant hearts and other organs.

Alzheimer’s or Dementia. What’s the Difference?

Talk recorded by CureTalks on August 8, 2018 at 3 pm ET

Alzheimer’s Disease and frontotemporal dementia (FTD) are two of the most common neurodegenerative conditions in the United States, but they are often misdiagnosed for each other. In reality, they are two different diseases that have varying effects on behavior and require different therapies.

In the following interview, Penn Medicine neurologists Murray Grossman, MD, EdD, and David Wolk, MD, discuss the similarities and differences between Alzheimer’s and FTD, along with related risks, diagnostic tests, progression stages, treatments and clinical trials.

Reversing Blindness with New FDA Approved Retinal Gene Therapy

Talk recorded by CureTalks on June 12, 2018 at 1 pm ET

In December 2017, the FDA approved the first ever DNA-altering gene therapy that can reverse an inherited form of progressive blindness. The gene therapy, called Luxturna, was developed by Jean Bennett, MD, PhD, and Albert M. Maguire, MD, spouses and co-directors of the Center for Advanced Retinal and Ocular Therapeutics at Penn Medicine.

In the following interview, the couple discusses the 25 years of work that went into the therapy and how the treatment is able to improve lost vision. 

Beating Leukemia with Groundbreaking CAR-T Cell Therapy

Talk recorded by CureTalks on April 25, 2018 at 3 pm ET

Listen to Stephan Grupp, MDdiscuss CAR-T cell therapy, an immunotherapy treatment that uses a patient's own genetically altered immune cells to fight cancer.

Dr. Grupp was part of the team that treated the first child, Emily Whitehead, with CAR-T cell therapy. Emily had end-stage leukemia and is now more than five years cancer free. Her father, Tom Whitehead, also discusses CAR-T and his family's experience during the chat.

Dr. Carl June's CAR-T Cell Journey and the Cancer Treatment Revolution

Talk recorded by CureTalks on November 15, 2017 at 1 pm ET

FDA approval of the breakthrough CAR-T cell therapy for cancer brings the first approved gene therapy treatment to the United States. It reprograms the body's own immune system to recognize and kill cancer cells.

Carl June, MD, is one of the pioneers of CAR-T cell research and leads the Penn Medicine team responsible for the historic FDA approval. Listen to Dr. June discuss the nuances of the treatment and what the future may hold for cancer patients.

How Will New Imaging Techniques and Genomic Tests Help In Diagnosis and Management of Prostate Cancer?

Talk recorded by CureTalks on February 9, 2016 at 6 pm ET

In this CureTalks interview, David Lee, MD, FACS, Chief of Urology at Penn Medicine, talks about recent advances in prostate cancer that have led to the discovery of new imaging and genomic tests. These tests and techniques can help patients make more informed decisions regarding their prostate cancer diagnosis, treatments and management options.

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