Penn Medicine Provider
About me
- Course Director, Annual Penn Brain Tumor CME
- Site Director, Perelman School of Medicine Surgery Rotation - Neurosurgery at HUP
- Director, Neurosurgery Medical Student Education
- Professor CE of Neurosurgery
Education and training
- Medical School: Harvard University
- Residency: Massachusetts General Hospital
- Fellowship: NewYork-Presbyterian/Weill Cornell Medical Center
- Fellowship: University of California, Los Angeles
What my patients think about me
30 reviews
Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.
October 2020
We appreciate the top notch professionals in this office. Every level of care was excellent
September 2020
Dr Brem was awesome.
March 2020
constantly interrupted from explaining my condition to answer cellphone
January 2020
again the staff are very friendly and helpful
My Locations
Penn Neuroscience Center - Neurosurgery
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: On the medical staff, but does not have privileges to treat patients in the hospital.
- Pennsylvania Hospital: On the medical staff, but does not have privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.
Qualifications and experience
- Neurological Surgery, 1983
- Advisory Board, Institute of Surgical Excellence, National
- American Brain Tumor Association, National
- American Brain Tumor Association, National
- American Brain Tumor Association-Discovery Grant Panel, National
- Appointed to NIH Review Panel, ZRG1 OTC-T(12)B, Small Business: Cancer Diagnostics and Treatments, National
- Central Brain Tumor Registry of the United States (CBTRUS), National
- Co-Chair, AACR/SNO-Neuro Tumor Club, National
- NCI Review Panel, Cancer Center Support Grant, P30, MD Anderson Comprehensive Cancer Center, National
- NCI Review Panel, Cancer Center Support Grant, P30, UCSF, National
- NCI SPORE Review Panel II, ZCA1 RPRB-0, National
- NCI-UCSF Cancer Center-Core Grant-CCSG-, National
- NIH / NCI, Brain Tumor Program Project Grant, National
- NIH Review Panel, ZRG1 OTC-T(12)B, Small Business: Cancer Diagnostics and Treatments, National
- NIH/NCATS Bench Testing Therapeutic/Indication Pairing Strategies (HU2/UH3) Review Special Emphasis Panel, National
- NIH/NCATS-ZTR1 CI-6-New Therapeutic Uses (NU) X02 Special Emphasis Panel-Grant Review, National
- NIH/NCI Spore Review-ZCA1 RPRB-7(MI) Group, National
- NIH-NCI, Brain Tumor SPORE (P50), ZCA1 RPRB-7 (MI),, National
- Society of Neuro-Oncology, National
- Penn Brain and Spinal Cord Tumors Program
- Penn Brain Tumor Center
Treatments and Conditions
My research
Brem S, Hoch MJ. Commentary: Resting State Functional Networks in Gliomas: Validation With Direct Electrical Stimulation Using a New Tool for Planning Brain Resections , Neurosurgery: 2024
Guo J, Fathi Kazerooni A, Toorens E, Akbari H, Yu F, Sako C, Mamourian E, Shinohara RT, Koumenis C, Bagley SJ, Morrissette JJD, Binder ZA, Brem S, Mohan S, Lustig RA, O'Rourke DM, Ganguly T, Bakas S, Nasrallah MP, Davatzikos C. Integrating imaging and genomic data for the discovery of distinct glioblastoma subtypes: a joint learning approach , Sci Rep, 14: 2024,4922
Bagley SJ, Binder ZA, Lamrani L, Marinari E, Desai AS, Nasrallah MP, Maloney E, Brem S, Lustig RA, Kurtz G, Alonso-Basanta M, Bonté PE, Goudot C, Richer W, Piaggio E, Kothari S, Guyonnet L, Guerin CL, Waterfall JJ, Mohan S, Hwang WT, Tang OY, Logun M, Bhattacharyya M, Markowitz K, Delman D, Marshall A, Wherry EJ, Amigorena S, Beatty GL, Brogdon JL, Hexner E, Migliorini D, Alanio C, O'Rourke DM. Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial , Nat Cancer, 5: 2024,517-531
Lu Y, Lee J, Li J, Allu SR, Wang J, Kim H, Bullaughey KL, Fisher SA, Nordgren CE, Rosario JG, Anderson SA, Ulyanova AV, Brem S, Chen HI, Wolf JA, Grady MS, Vinogradov SA, Kim J, Eberwine J. CHEX-seq detects single-cell genomic single-stranded DNA with catalytical potential , Nat Commun, 14: 2023,7346
de Godoy LL, Chawla S, Brem S, Mohan S. Taming Glioblastoma in "Real Time": Integrating Multimodal Advanced Neuroimaging/AI Tools Towards Creating a Robust and Therapy Agnostic Model for Response Assessment in Neuro-Oncology , Clin Cancer Res, 29: 2023,2588-2592
Richardson TE, Yokoda RT, Rashidipour O, Vij M, Snuderl M, Brem S, Hatanpaa KJ, McBrayer SK, Abdullah KG, Umphlett M, Walker JM, Tsankova NM. Mismatch repair protein mutations in isocitrate dehydrogenase (IDH)-mutant astrocytoma and IDH-wild-type glioblastoma , Neurooncol Adv, 5: 2023,vdad085
Sampson JH, Singh Achrol A, Aghi MK, Bankiewicz K, Bexon M, Brem S, Brenner A, Chandhasin C, Chowdhary S, Coello M, Ellingson BM, Floyd JR, Han S, Kesari S, Mardor Y, Merchant F, Merchant N, Randazzo D, Vogelbaum M, Vrionis F, Wembacher-Schroeder E, Zabek M, Butowski N. Targeting the IL4 receptor with MDNA55 in patients with recurrent glioblastoma: Results of a phase IIb trial , Neuro Oncol, 25: 2023,1085-1097
Nabavizadeh A, Bagley SJ, Doot RK, Ware JB, Young AJ, Ghodasara S, Zhao C, Anderson H, Schubert E, Carpenter EL, Till J, Henderson F Jr, Pantel AR, Chen HI, Lee JYK, Amankulor NM, O'Rourke DM, Desai A, Nasrallah MP, Brem S. Distinguishing Progression from Pseudoprogression in Glioblastoma Using (18)F-Fluciclovine PET , J Nucl Med, 64(6): 2023
de Godoy LL, Chawla S, Brem S, Wang S, O'Rourke DM, Nasrallah MP, Desai A, Loevner LA, Liau LM, Mohan S. Assessment of treatment response to dendritic cell vaccine in patients with glioblastoma using a multiparametric MRI-based prediction model , J Neurooncol, 163(1): 2023
Golkar E, Parker D, Brem S, Almairac F, Verma R. CrOssing fiber Modeling in the Peritumoral Area using dMRI (COMPARI) , bioRxiv: 2023