Stephen Bagley, MD, MSCE

Stephen J. Bagley, Meghan Logun, Joseph A. Fraietta, Xin Wang, Arati S. Desai, Linda J. Bagley, Ali Nabavizadeh, Danuta Jarocha, Rene Martins, Eileen Maloney, Lester Lledo, Carly Stein, Amy Marshall, Rachel Leskowitz, Julie K. Jadlowsky, Shannon Christensen, Bike Su Oner, Gabriela Plesa, Andrea Brennan, Vanessa Gonzalez, Fang Chen, Yusha Sun, Whitney Gladney, David Barrett, MacLean P. Nasrallah, Wei-Ting Hwang, Guo-Li Ming, Hongjun Song, Donald L. Siegel, Carl H. June, Elizabeth O. Hexner, Zev A. Binder & Donald M. O’Rourke Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results , Nat Med , 30(5): 2024,1320-1329

Stephen J Bagley, Zev A Binder, Lamia Lamrani, Eliana Marinari, Arati S Desai, MacLean P Nasrallah, Eileen Maloney, Steven Brem, Robert A Lustig, Goldie Kurtz, Michelle Alonso-Basanta, Pierre-Emmanuel Bonté, Christel Goudot, Wilfrid Richer, Eliane Piaggio, Shawn Kothari, Lea Guyonnet, Coralie L Guerin, Joshua J Waterfall, Suyash Mohan, Wei-Ting Hwang, Oliver Y Tang, Meghan Logun, Meghna Bhattacharyya, Kelly Markowitz, Devora Delman, Amy Marshall, E John Wherry, Sebastian Amigorena, Gregory L Beatty, Jennifer L Brogdon, Elizabeth Hexner, Denis Migliorini, Cecile Alanio, Donald M O'Rourke Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial , Nature Cancer, 5(3): 2024,517-531

Rifaquat Rahman; Steffen Ventz; Jon McDunn; Bill Louv; Irmarie Reyes-Rivera; Mei-Yin Polley; Stephen Bagley; Mustafa Khasraw; Timothy Cloughesy; Patrick Y. Wen; Brian Alexander; Lorenzo Trippa Leveraging External Data in the Design and Analysis of Clinical Trials in Neuro-Oncology , Lancet Oncology, 22(10): 2021,e456-e465

Kirit Singh, Kelly M. Hotchkiss, Ian F. Parney, John De Groot, Solmaz Sahebjam, Nader Sanai, Michael Platten, Evanthia Galanis, Michael Lim, Patrick Y. Wen, Giuseppe Minniti, Howard Colman, Timothy F. Cloughesy, Minesh P. Mehta, Marjolein Geurts, Isabel Arrillaga-Romany, Annick Desjardins, Kirk Tanner, Susan Short, David Arons, Elizabeth Duke, Wolfgang Wick, Stephen J. Bagley, David M. Ashley, Priya Kumthekar, Roel Verhaak, Anthony J. Chalmers, Anoop P. Patel, Colin Watts, Peter E. Fecci, Tracy T. Batchelor, Michael Weller, Michael A. Vogelbaum, Matthias Preusser, Mitchel S. Berger, Mustafa Khasraw Correcting the drug development paradigm for glioblastoma requires serial tissue sampling , Nat Med, 29(10): 2023,2402-2405

Yang F, Zhang D, Jian H, Ye J, Zhang L, Bagley SJ, Winkler J, Gong Y, Fan Y. Small-molecule toosendanin reverses macrophage-mediated immunosuppression to overcome glioblastoma resistance to immunotherapy , Science Translational Medicine, 15(683): 2023,eabq3558.

Stephen Bagley, Shawn Kothari, Rifaquat Rahman, Eudocia Lee, Gavin Dunn, Evanthia Galanis, Susan Chang, Louis Nabors, Manmeet Ahluwalia, Roger Stupp, Minesh Mehta, David Reardon, Stuart Grossman, Erik Sulman, John Sampson, Simon Khagi, Michael Weller, Timothy Cloughesy, Patrick Wen, and Mustafa Khasraw Glioblastoma Clinical Trials: A Summary of the Current Landscape and Opportunities for Improvement , Clinical Cancer Research, 28(4): 2022,594-602

Fan Yang, Zhenqiang He, Hao Duan, Duo Zhang, Juehui Li, Huijuan Yang, Jay F Dorsey, Wei Zou, S Ali Nabavizadeh, Stephen J Bagley, Kalil Abdullah, Steven Brem, Lin Zhang, Xiaowei Xu, Katelyn T Byrne, Robert H Vonderheide, Yanqing Gong, Yi Fan Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40 , Nature Communications, 12(1): 2021,3424

Bagley SJ, Nabavizadeh SA, Mays JJ, Till JE, Ware JB, Levy S, Sarchiapone W, Hussain J, Prior T, Guiry S, Christensen T, Yee SS, Nasrallah MP, Morrissette JJD, Binder ZA, O'Rourke DM, Cucchiara AJ, Brem S, Desai AS, Carpenter EL Clinical Utility of Plasma Cell-Free DNA in Adult Patients With Newly Diagnosed Glioblastoma: A Pilot Prospective Study , Clin Cancer Res , 26(2): 2020,397-407

Nicholas Mikolajewicz, Patricia P Yee, Debarati Bhanja, Mara Trifoi, Alexandra M Miller, Philippe Metellus, Stephen J Bagley, Leonora Balaj, Leonardo J M de Macedo Filho, Brad E Zacharia, Dawit Aregawi, Michael Glantz, Michael Weller, Manmeet S Ahluwalia, Thomas Kislinger, Alireza Mansouri Systematic Review of Cerebrospinal Fluid Biomarker Discovery in Neuro-Oncology: A Roadmap to Standardization and Clinical Application , J Clin Oncol , 42(16): 2024,1961-1974

Foster JB, Koptyra MP, Bagley SJ. Recent developments in blood biomarkers in neuro-oncology. , Curr Neurol Neurosci Rep , 23(12): 2023,857-867