Stephen Bagley, MD, MSCE
Medical Oncology
Accepting new patients
Sees patients age 18 and up
Abramson Cancer Center Perelman 2nd Floor West
Make an appointmentCall 215-615-5858
Headshot of Stephen Bagley, MD, MSCE
Penn Medicine Provider

About me

  • Section Chief, Neuro-Oncology, Hematology-Oncology
  • Associate Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
  • Assistant Professor of Medicine in Neurosurgery

Education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: University of Pennsylvania Health System
  • Fellowship: University of Pennsylvania Health System

What my patients think about me

Average Rating

478 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
March 2026
dr. bagley is fantastic.
Anonymous
March 2026
friendly, proactive, cutting edge, knowledgeable
Anonymous
March 2026
friendly
Anonymous
March 2026
i was suppose to have two appts today but the second appt was scheduled for 4:30 it was after 5 pm before his nurse came in to pacify us i guess but it was already too late.... she really couldn't answer the questions i had and couldn't even show me the results of the mri which i usually see when i press my way all the way to hup for that info since my surgery in 2,022. her coming in at that time was not e appreciated as expected because no one had the professional courtesy to let us know that dr bagley was tied up with another pt which we surely understand how that can happen and so what happen to the days that he brought other residents into the room for my post mri visits. we live a distance away and depend on the train to get us there and home to continue our other obligations thru the week that we had to cancel because of sitting for an hour without info so when dr bagley finally could break away to see my husband and i for a quick few minutes we then felt that there was little time to ask questions but were very pleased to hear that there were no more changes or growths from mri results. so tonight we exhale and are thankful that no more surgery was needed at this time and no more suggestions about a new medication nor oxygen chamber

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Bagley is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Stephen J. Bagley, Meghan Logun, Joseph A. Fraietta, Xin Wang, Arati S. Desai, Linda J. Bagley, Ali Nabavizadeh, Danuta Jarocha, Rene Martins, Eileen Maloney, Lester Lledo, Carly Stein, Amy Marshall, Rachel Leskowitz, Julie K. Jadlowsky, Shannon Christensen, Bike Su Oner, Gabriela Plesa, Andrea Brennan, Vanessa Gonzalez, Fang Chen, Yusha Sun, Whitney Gladney, David Barrett, MacLean P. Nasrallah, Wei-Ting Hwang, Guo-Li Ming, Hongjun Song, Donald L. Siegel, Carl H. June, Elizabeth O. Hexner, Zev A. Binder & Donald M. O’Rourke Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results , Nat Med , 30(5): 2024,1320-1329

Stephen J Bagley, Zev A Binder, Lamia Lamrani, Eliana Marinari, Arati S Desai, MacLean P Nasrallah, Eileen Maloney, Steven Brem, Robert A Lustig, Goldie Kurtz, Michelle Alonso-Basanta, Pierre-Emmanuel Bonté, Christel Goudot, Wilfrid Richer, Eliane Piaggio, Shawn Kothari, Lea Guyonnet, Coralie L Guerin, Joshua J Waterfall, Suyash Mohan, Wei-Ting Hwang, Oliver Y Tang, Meghan Logun, Meghna Bhattacharyya, Kelly Markowitz, Devora Delman, Amy Marshall, E John Wherry, Sebastian Amigorena, Gregory L Beatty, Jennifer L Brogdon, Elizabeth Hexner, Denis Migliorini, Cecile Alanio, Donald M O'Rourke Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial , Nature Cancer, 5(3): 2024,517-531

Rifaquat Rahman; Steffen Ventz; Jon McDunn; Bill Louv; Irmarie Reyes-Rivera; Mei-Yin Polley; Stephen Bagley; Mustafa Khasraw; Timothy Cloughesy; Patrick Y. Wen; Brian Alexander; Lorenzo Trippa Leveraging External Data in the Design and Analysis of Clinical Trials in Neuro-Oncology , Lancet Oncology, 22(10): 2021,e456-e465

Kirit Singh, Kelly M. Hotchkiss, Ian F. Parney, John De Groot, Solmaz Sahebjam, Nader Sanai, Michael Platten, Evanthia Galanis, Michael Lim, Patrick Y. Wen, Giuseppe Minniti, Howard Colman, Timothy F. Cloughesy, Minesh P. Mehta, Marjolein Geurts, Isabel Arrillaga-Romany, Annick Desjardins, Kirk Tanner, Susan Short, David Arons, Elizabeth Duke, Wolfgang Wick, Stephen J. Bagley, David M. Ashley, Priya Kumthekar, Roel Verhaak, Anthony J. Chalmers, Anoop P. Patel, Colin Watts, Peter E. Fecci, Tracy T. Batchelor, Michael Weller, Michael A. Vogelbaum, Matthias Preusser, Mitchel S. Berger, Mustafa Khasraw Correcting the drug development paradigm for glioblastoma requires serial tissue sampling , Nat Med, 29(10): 2023,2402-2405

Yang F, Zhang D, Jian H, Ye J, Zhang L, Bagley SJ, Winkler J, Gong Y, Fan Y. Small-molecule toosendanin reverses macrophage-mediated immunosuppression to overcome glioblastoma resistance to immunotherapy , Science Translational Medicine, 15(683): 2023,eabq3558.

Stephen Bagley, Shawn Kothari, Rifaquat Rahman, Eudocia Lee, Gavin Dunn, Evanthia Galanis, Susan Chang, Louis Nabors, Manmeet Ahluwalia, Roger Stupp, Minesh Mehta, David Reardon, Stuart Grossman, Erik Sulman, John Sampson, Simon Khagi, Michael Weller, Timothy Cloughesy, Patrick Wen, and Mustafa Khasraw Glioblastoma Clinical Trials: A Summary of the Current Landscape and Opportunities for Improvement , Clinical Cancer Research, 28(4): 2022,594-602

Fan Yang, Zhenqiang He, Hao Duan, Duo Zhang, Juehui Li, Huijuan Yang, Jay F Dorsey, Wei Zou, S Ali Nabavizadeh, Stephen J Bagley, Kalil Abdullah, Steven Brem, Lin Zhang, Xiaowei Xu, Katelyn T Byrne, Robert H Vonderheide, Yanqing Gong, Yi Fan Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40 , Nature Communications, 12(1): 2021,3424

Bagley SJ, Nabavizadeh SA, Mays JJ, Till JE, Ware JB, Levy S, Sarchiapone W, Hussain J, Prior T, Guiry S, Christensen T, Yee SS, Nasrallah MP, Morrissette JJD, Binder ZA, O'Rourke DM, Cucchiara AJ, Brem S, Desai AS, Carpenter EL Clinical Utility of Plasma Cell-Free DNA in Adult Patients With Newly Diagnosed Glioblastoma: A Pilot Prospective Study , Clin Cancer Res , 26(2): 2020,397-407

Nicholas Mikolajewicz, Patricia P Yee, Debarati Bhanja, Mara Trifoi, Alexandra M Miller, Philippe Metellus, Stephen J Bagley, Leonora Balaj, Leonardo J M de Macedo Filho, Brad E Zacharia, Dawit Aregawi, Michael Glantz, Michael Weller, Manmeet S Ahluwalia, Thomas Kislinger, Alireza Mansouri Systematic Review of Cerebrospinal Fluid Biomarker Discovery in Neuro-Oncology: A Roadmap to Standardization and Clinical Application , J Clin Oncol , 42(16): 2024,1961-1974

Foster JB, Koptyra MP, Bagley SJ. Recent developments in blood biomarkers in neuro-oncology. , Curr Neurol Neurosci Rep , 23(12): 2023,857-867

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