Penn Medicine Provider
Sleep Medicine
Ron C. Anafi, MD, PhD
4.7
(116)
Accepting new patients
Sees patients age 18 and up
Penn Sleep Center Market Street
Schedule onlineCall 215-662-7772

About me

  • Associate Professor of Medicine (Sleep Medicine) at the Hospital of the University of Pennsylvania

Education and training

  • Medical School: University of Minnesota Medical School
  • Residency: University of Vermont Medical Center
  • Fellowship: Hospital of the University of Pennsylvania

What my patients think about me

Average Rating
4.7

116 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

May 2025
5.0
5.0
would definitely recommend
April 2025
5.0
5.0
very fine physician
April 2025
5.0
5.0
listened, laid out the options, did not push an agenda, answered questions
April 2025
5.0
5.0
the dr was nice and answered all my questions

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
Dr. Anafi is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Anafi RC, Francey LJ, Hogenesch JB, Kim J CYCLOPS reveals human transcriptional rhythms in health and disease , Proceedings of the National Academy of Sciences of the United States of America, 114(20): 2017,5312-5317

Li SY, Hammarlund JA, Wu G, Lian JW, Howell SJ, Clarke RB, Adamson AD, Gonçalves CF, Hogenesch JB, Anafi RC, Meng QJ. Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in luminal A breast cancer , Proc Natl Acad Sci U S A, 121: 2024,e2311854121

Anafi RC, Kayser MS, Raizen DM Exploring phylogeny to find the function of sleep , Nature Reviews. Neuroscience, 20(2): 2019,109-116

Ruben MD, Wu G, Smith DF, Schmidt RE, Francey LJ, Lee YY, Anafi RC, Hogenesch JB A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine , Science Translational Medicine, 10(458): 2018,eaat8806

Ben-Zvi D, Meoli L, Abidi WM, Nestoridi E, Panciotti C, Castillo E, Pizarro P, Shirley E, Gourash WF, Thompson CC, Munoz R, Clish CB, Anafi RC, Courcoulas AP, Stylopoulos N Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species , Cell Metabolism, 28(2): 2018,310-323.e6

Foteinou PT, Venkataraman A, Francey LJ, Anafi RC, Hogenesch JB, Doyle FJ Computational and experimental insights into the circadian effects of SIRT1 , Proceedings of the National Academy of Sciences of the United States of America, 115(45): 2018,11643-11648

Krishnaiah SY, Wu G, Altman B, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM Clock regulation of metabolites reveals coupling between transcription and metabolism , Cell Metabolism, 25(4): 2017,961-974.e4

Arnardottir ES, Nikonova EV, Shockley KR, Podtelezhnikov AA, Anafi RC, Tanis KQ, Maislin G, Stone DJ, Renger JJ, Winrow CJ, Pack AI Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation , Sleep, 37(10): 2014,1589-1600

Zhang R, Podtelezhnikov AA, Hogenesch JB, Anafi RC Discovering biology in periodic data through Phase Set Enrichment Analysis (PSEA) , Journal of Biological Rhythms, 31(3): 2016,244-257

Anafi RC, Lee Y, Sato TK, Venkataraman A, Ramanathan C, Kavakli IH, Hughes ME, Baggs JE, Growe J, Liu AC, Kim J, Hogenesch J Machine learning helps identify CHRONO as a circadian clock component , PLoS Biology, 12(4): 2014,e1001840