Penn Medicine Provider
Robert J. Lee, PhD
Accepting new patients
Sees patients age 18 and up

About me

  • Associate Professor of Otorhinolaryngology: Head and Neck Surgery

Insurance accepted

My Locations

Qualifications and experience

Treatments and Conditions

My research

Lee, RJ., and Cohen NA Innate immune function in chronic rhinosinusitis , Journal of Allergy and Clinical Immunology, 155: 2025,1472-1474


Kouakou YI, Thompson JC, Tan LH, Miller ZA, Ma RZ, Adappa ND, Palmer JN, Cohen NA, and <b>Lee RJ</b> Hops bitter beta-acids have antibacterial effects against sinonasal <i>Staphylococcus aureus</i> but also induce sinonasal cilia and mitochondrial dysfunction , International Forum of Allergy and Rhinology, 15: 2025,287-302


Miller ZA, Mueller A, Kim TB, Jolivert JF, Ma RZ, Muthuswami S, Park A, McMahon DB, Nead KT, Carey RM, <b>Lee RJ</b>. Lidocaine Induces Apoptosis in Head and Neck Squamous Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14 , Cell Reports: 2023


Kouakou YI and <b>Lee RJ</b> Interkingdom detection of bacterial quorum sensing molecules by mammalian taste receptors , Microorganisms, 11(5): 2023,1295


Carey RM, Adappa ND, Palmer JN, <b>Lee RJ</b> Loss of CFTR Function Is Associated With Reduced Bitter Taste Receptor-Stimulated Nitric Oxide Innate Immune Responses in Nasal Epithelial Cells and Macrophages , Frontiers in Immunology, 14: 2023,1096242


Carey RM, McMahon DB, Miller ZA, Kim TB, Rajasekaran K, Gopallawa I, Newman JG, Basu D, Nead KT, White EA, <b>Lee RJ</b> T2R Bitter Taste Receptors Regulate Apoptosis and May Be Associated with Survival in Head and Neck Squamous Cell Carcinoma , Molecular Oncology, 16(7): 2022,1474-1492


McMahon DB, Kuek LE, Johnson ME, Johnson PO, Horn RLJ, Carey RM, Adappa ND, Palmer JN, and <b>Lee RJ</b> The Bitter End: T2R Bitter Receptor Agonists Elevate Nuclear Calcium and Induce Apoptosis in Non-Ciliated Airway Epithelial Cells , Cell Calcium, 101: 2022,102499


McMahon DB, Carey RM, Kohanski MA, Adappa ND, Palmer JN, and <b>Lee RJ</b> PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by <i>Pseudomonas aeruginosa</i> , American Journal of Physiology-Lung Cellular and Molecular Physiology, 320(5): 2021,L845-L879


Gopallawa I, Freund JR, and <b>Lee RJ</b> Bitter Taste Receptors Stimulate Phagocytosis in Human Macrophages Through Calcium, Nitric Oxide, and Cyclic-GMP Signaling , Cellular and Molecular Life Sciences, 78(1): 2021,271-286


Kuek L, and <b>Lee RJ</b> First Contact: The Role of Respiratory Cilia in Host-Pathogen Interactions in the Airways , American Journal of Physiology-Lung Cellular and Molecular Physiology, 319(4): 2020,L603-L619