Robert J. Lee, PhD

Accepting new patients
Sees patients age 18 and up
Penn Medicine Provider

About me

  • Associate Professor of Otorhinolaryngology: Head and Neck Surgery

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Qualifications and experience

Treatments and Conditions

Research

Publications

Lee, RJ., and Cohen NA Innate immune function in chronic rhinosinusitis , Journal of Allergy and Clinical Immunology, 155: 2025,1472-1474


Kouakou YI, Thompson JC, Tan LH, Miller ZA, Ma RZ, Adappa ND, Palmer JN, Cohen NA, and <b>Lee RJ</b> Hops bitter beta-acids have antibacterial effects against sinonasal <i>Staphylococcus aureus</i> but also induce sinonasal cilia and mitochondrial dysfunction , International Forum of Allergy and Rhinology, 15: 2025,287-302


Miller ZA, Mueller A, Kim TB, Jolivert JF, Ma RZ, Muthuswami S, Park A, McMahon DB, Nead KT, Carey RM, <b>Lee RJ</b>. Lidocaine Induces Apoptosis in Head and Neck Squamous Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14 , Cell Reports: 2023


Kouakou YI and <b>Lee RJ</b> Interkingdom detection of bacterial quorum sensing molecules by mammalian taste receptors , Microorganisms, 11(5): 2023,1295


Carey RM, Adappa ND, Palmer JN, <b>Lee RJ</b> Loss of CFTR Function Is Associated With Reduced Bitter Taste Receptor-Stimulated Nitric Oxide Innate Immune Responses in Nasal Epithelial Cells and Macrophages , Frontiers in Immunology, 14: 2023,1096242


Carey RM, McMahon DB, Miller ZA, Kim TB, Rajasekaran K, Gopallawa I, Newman JG, Basu D, Nead KT, White EA, <b>Lee RJ</b> T2R Bitter Taste Receptors Regulate Apoptosis and May Be Associated with Survival in Head and Neck Squamous Cell Carcinoma , Molecular Oncology, 16(7): 2022,1474-1492


McMahon DB, Kuek LE, Johnson ME, Johnson PO, Horn RLJ, Carey RM, Adappa ND, Palmer JN, and <b>Lee RJ</b> The Bitter End: T2R Bitter Receptor Agonists Elevate Nuclear Calcium and Induce Apoptosis in Non-Ciliated Airway Epithelial Cells , Cell Calcium, 101: 2022,102499


McMahon DB, Carey RM, Kohanski MA, Adappa ND, Palmer JN, and <b>Lee RJ</b> PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by <i>Pseudomonas aeruginosa</i> , American Journal of Physiology-Lung Cellular and Molecular Physiology, 320(5): 2021,L845-L879


Gopallawa I, Freund JR, and <b>Lee RJ</b> Bitter Taste Receptors Stimulate Phagocytosis in Human Macrophages Through Calcium, Nitric Oxide, and Cyclic-GMP Signaling , Cellular and Molecular Life Sciences, 78(1): 2021,271-286


Kuek L, and <b>Lee RJ</b> First Contact: The Role of Respiratory Cilia in Host-Pathogen Interactions in the Airways , American Journal of Physiology-Lung Cellular and Molecular Physiology, 319(4): 2020,L603-L619