Penn Medicine Provider
Yanqing Anna Gong, MS, PhD

About me

  • Research Associate Professor of Medicine (Translational Medicine and Human Genetics)

Qualifications and experience

My research

Ni H, Reitman ZJ, Zou W, Akhtar MN, Paul R, Huang M, Zhang D, Zheng H, Zhang R, Ma R, Ngo G, Zhang L, Diffenderfer ES, Motlagh SAO, Kim MM, Minn AJ, Dorsey JF, Foster JB, Metz J, Koumenis C, Kirsch DG*, Gong Y*, Fan Y* FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy , Nature Cancer, 6(3): 2025,460-473


Xinye Ashley Zhao, Thomas Williamson, Yanqing Gong, *, Jonathan A. Epstein, * & Yi Fan* Immunomodulatory therapy for ischemic heart diseases , Circulation, 150 (13): 2024


Yang F, Akhtar N, Zhang D, El-Mayta R, Shin J, Dorsey JF, Zhang L, Xu X, Guo W, Bagley SJ, Fuchs SY, Koumenis C, Lathia JD, Mitchell MJ, Gong Y*, & Fan Y* An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma , Science Advances , 10(9):eadj4678: 2024


Huang M., Yang F., Zhang D., Lin M., Duan H. EI-Mayta R., Zhang L., Qin L., Shewale S., Pei L., Mitchell M., Rader D., Fan Y*., Gong Y*. Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction , Nature Cardiovasc. Res. : 2022


Wang L. Yao L. Duan H. Yang F. Lin M. Zhang R. He, Z. Ahn J. Fan Y. Qin L*. Gong Y*. Plasminogen Regulates Fracture Repair by Promoting the Functions of Periosteal Mesenchymal Progenitors , Journal of Bone and Mineral Research , 36(11): 2021


Yang F, He Z, Duan H, Zhang D, Li J, Yang H, Dorsey JF, Zou W, Nabavizadeh SA, Bagley SJ, Abdullah K, Brem S, Zhang L, Xu X, Byrne KT, Vonderheide RH*, Gong Y*, & Fan Y*. Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40. , Nat. Commun., 12(1): 2021


Ma W., Wang Y., Zhang R., Yang F., Zhang D., Huang, M., Zhang L., Dorsey J., Binder Z., O'Rourke D., Fraietta J., Gong Y*., Fan Y*., Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma. , Nature Cancer: 2020


Duan H, He Z, Lin M, Wang Y, Yang F, Mitteer, R, Kim H, Yeo E, Han H, Qin L, Fan Y, and Gong Y. Plasminogen regulates mesenchymal stem cellmediated tissue repair after ischemia through cyr61 activation , JCI insight, 5(15): 2020


Gong Y*, Zhao Y, Li Y, Fan Y, Hoover-Plow J Plasminogen regulates cardiac repair after myocardial infarction through its noncanonical function in stem cell homing to the infarcted heart. , J Am Coll Cardiol, 63(25): 2014 ,2862-2872


Gong Y, Hart E, Shchurin A, Hoover-Plow J Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice. , J Clin Invest, 118(9): 2008,3012-24