About me
- Professor of Pathology and Laboratory Medicine
My Locations
Qualifications and experience
- American Association for Cancer Research, National
- American Association of Immunologists, National
- American Chemical Society, National
- American Society for Biochemistry and Molecular Biology, National
- American Society for Hematology, National
- American Society for Microbiology, National
- American Society of Gene & Cell Therapy, National
- American Society of Nephrology, National
- American Society of Transplantation, National
- American Thoracic Society, National
- International Chemical Biology Society, International
- International Hand and Composite Tissue Allotransplantation Society, International
- International Pancreas and Islet Transplant Association, International
- International Society of Nephrology, International
- Oligonucleotide Therapeutics Society, International
- Society for Immunotherapy of Cancer, National
- The Transplantation Society, International
- Transplantation Society of Australia and New Zealand, National
- Trisomy 21 Research Society, International
- University of Pennsylvania, Local
Treatments and Conditions
My research
Yardeni T, Olali AZ, Chen HW, Wang L, Halton J, Zenab A, Morrow R, Butic A, Murdock DG, Waymire KG, MacGregor G, Boursi B, Beier U, Hancock WW, Wallace DC. Mitochondrial DNA lineages determine tumor progression through T cell reactive oxygen signaling , Proceedings of the National Academy of Sciences, 122: 2025,e2417252121
Pace J, Goddard L, Hong C, Wang L, Yang J, Chen M, Xu Y, Dominguez M, Gao S, Chen X, Mericko P, Yu W, Tan K, Hancock WW, Ferrari G, Kahn ML Hemodynamic forces prevent myxomatous valve disease through KLF2/4 signaling , Journal of Clinical Investigation: 2025
Concors SJ, Hernandez PT, O’Brien C, DePaolo J, Murken DR, Aufhauser DD, Wang Z, Xiong Y, Krumeich L, Ge G, Beier UH, Bhatti TR, Kozikowski AP, Avelar L, Kurz T, Hancock WW, Levine MH. Differential effects of HDAC6 inhibition versus knockout during hepatic ischemia reperfusion injury highlight importance of HDAC6 C-terminal zinc-finger ubiquitin-binding domain. , Transplantation: 2024,In press
Akimova T, Wang L, Bartosh Z, Christensen L, Eruslanov E, Singhal S, Aishwarya V, Hancock WW. Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity. , Frontiers in Immunology, 15: 2024,1426657
Christensen LM, Akimova T, Wang L, Han R, Samanta A, Di Giorgio E, Hancock WW. T-regulatory cells require Sin3a for stable expression of Foxp3. , Frontiers in Immunology, 15: 2024,1444937
Thomas RM, Pahl MC, Wang L, Grant SFA, Hancock WW, Wells AD. Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function. , eLife: 2024,RP91392
Cravedi P, Riella LV, Ford M, Valujskikh A, Menon MC, Kirk AD, Alegre ML, Feng S, Kehn P, Najafian N, Hancock W, Heeger PS, Maltzman J, Mannon RB, Nadig S, Odim J, Turnquist H, Shaw J, West L, Luo X, Chong A, Bromberg J, on behalf of the AST COTS MOuse MOdels in Transplantation (MOMOT) work group. Advancing mouse models for transplantation research. , American Journal of Transplantation: 2024,https://doi.org/10.1016/j.ajt.2024.01.006
Patterson KC, Miller WT, Hancock WW, Akimova T. FOXP3+ regulatory T cells are associated with the severity and prognosis of sarcoidosis. , Frontiers in Immunology, 14: 2023,1301991
Lax E, Do Carmo S, Enuka Y, Sapozhnikov DM, Welikovitch LA, Mahmood N, Rabbani SA, Wang L, Britt JP, Hancock WW, Yarden Y, Szyf M. Methyl-CpG binding domain 2 (Mbd2) is an epigenetic regulator of autism-risk genes and cognition. , Translational Psychiatry, 13: 2023,259
Hernandez P, O’Brien C, Concors SJ, Wang Z, Ge G, Hancock WW, Levine MH. The selective estrogen receptor modulator, Raloxifene, is protective against renal ischemia reperfusion injury. , Transplantation, 106: 2022,2166-2171